Li X - Search Results

1

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.

Chang LS, Oblinger JL, Smith AE, Ferrer M, Angus SP, Hawley E, Petrilli AM, Beauchamp RL, Riecken LB, Erdin S, Poi M, Huang J, Bessler WK, Zhang X, Guha R, Thomas C, Burns SS, Gilbert TSK, Jiang L, Li X, Lu Q, Yuan J, He Y, Dixon SAH, Masters A, Jones DR, Yates CW, Haggarty SJ, La Rosa S, Welling DB, Stemmer-Rachamimov AO, Plotkin SR, Gusella JF, Guinney J, Morrison H, Ramesh V, Fernandez-Valle C, Johnson GL, Blakeley JO, Clapp DW; Synodos for NF2 Consortium. Chang LS, et al. Among authors: li x. PLoS One. 2021 Jul 15;16(7):e0252048. doi: 10.1371/journal.pone.0252048. eCollection 2021. PLoS One. 2021. PMID: 34264955 Free PMC article.

2

Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells.

Munchhof AM, Li F, White HA, Mead LE, Krier TR, Fenoglio A, Li X, Yuan J, Yang FC, Ingram DA. Munchhof AM, et al. Among authors: li f, li x. Hum Mol Genet. 2006 Jun 1;15(11):1858-69. doi: 10.1093/hmg/ddl108. Epub 2006 Apr 28. Hum Mol Genet. 2006. PMID: 16648142

3

Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling.

Yang FC, Chen S, Clegg T, Li X, Morgan T, Estwick SA, Yuan J, Khalaf W, Burgin S, Travers J, Parada LF, Ingram DA, Clapp DW. Yang FC, et al. Among authors: li x. Hum Mol Genet. 2006 Aug 15;15(16):2421-37. doi: 10.1093/hmg/ddl165. Epub 2006 Jul 11. Hum Mol Genet. 2006. PMID: 16835260 Free PMC article.

4

Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.

Yang FC, Chen S, Robling AG, Yu X, Nebesio TD, Yan J, Morgan T, Li X, Yuan J, Hock J, Ingram DA, Clapp DW. Yang FC, et al. Among authors: li x. J Clin Invest. 2006 Nov;116(11):2880-91. doi: 10.1172/JCI29092. Epub 2006 Oct 19. J Clin Invest. 2006. PMID: 17053831 Free PMC article.

5

Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy.

Nebesio TD, Ming W, Chen S, Clegg T, Yuan J, Yang Y, Estwick SA, Li Y, Li X, Hingtgen CM, Yang FC. Nebesio TD, et al. Among authors: li y, li x. Glia. 2007 Apr 1;55(5):527-36. doi: 10.1002/glia.20482. Glia. 2007. PMID: 17236191

6

Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.

Yan J, Chen S, Zhang Y, Li X, Li Y, Wu X, Yuan J, Robling AG, Kapur R, Chan RJ, Yang FC. Yan J, et al. Among authors: li y, li x. Hum Mol Genet. 2008 Apr 1;17(7):936-48. doi: 10.1093/hmg/ddm366. Epub 2007 Dec 18. Hum Mol Genet. 2008. PMID: 18089636

7

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.

Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, Robertson K, Hutchins G, Parada LF, Clapp DW. Yang FC, et al. Among authors: li y, li x. Cell. 2008 Oct 31;135(3):437-48. doi: 10.1016/j.cell.2008.08.041. Cell. 2008. PMID: 18984156 Free PMC article.

8

Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.

Chen S, Burgin S, McDaniel A, Li X, Yuan J, Chen M, Khalaf W, Clapp DW, Yang FC. Chen S, et al. Among authors: li x. Am J Pathol. 2010 Dec;177(6):3125-32. doi: 10.2353/ajpath.2010.100369. Epub 2010 Oct 29. Am J Pathol. 2010. PMID: 21037083 Free PMC article.

9

Primary osteopathy of vertebrae in a neurofibromatosis type 1 murine model.

Zhang W, Rhodes SD, Zhao L, He Y, Zhang Y, Shen Y, Yang D, Wu X, Li X, Yang X, Park SJ, Chen S, Turner C, Yang FC. Zhang W, et al. Among authors: li x. Bone. 2011 Jun 1;48(6):1378-87. doi: 10.1016/j.bone.2011.03.760. Epub 2011 Mar 23. Bone. 2011. PMID: 21439418 Free PMC article.

10

Kinase suppressor of Ras (KSR1) modulates multiple kit-ligand-dependent mast cell functions.

Chen M, Burgin S, Staser K, He Y, Li X, Robinson M, Jiang L, Chan RJ, Ingram D, Clapp DW. Chen M, et al. Among authors: li x. Exp Hematol. 2011 Oct;39(10):969-76. doi: 10.1016/j.exphem.2011.06.009. Epub 2011 Jul 1. Exp Hematol. 2011. PMID: 21726514 Free PMC article.

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