Höcker B - Search Results

1

The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.

Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. Among authors: hocker b. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.

2

Potential of fragment recombination for rational design of proteins.

Eisenbeis S, Proffitt W, Coles M, Truffault V, Shanmugaratnam S, Meiler J, Höcker B. Eisenbeis S, et al. Among authors: hocker b. J Am Chem Soc. 2012 Mar 7;134(9):4019-22. doi: 10.1021/ja211657k. Epub 2012 Feb 23. J Am Chem Soc. 2012. PMID: 22329686 Free article.

3

A highly stable protein chimera built from fragments of different folds.

Shanmugaratnam S, Eisenbeis S, Höcker B. Shanmugaratnam S, et al. Among authors: hocker b. Protein Eng Des Sel. 2012 Nov;25(11):699-703. doi: 10.1093/protein/gzs074. Epub 2012 Oct 18. Protein Eng Des Sel. 2012. PMID: 23081840

4

Change in protein-ligand specificity through binding pocket grafting.

Scheib U, Shanmugaratnam S, Farías-Rico JA, Höcker B. Scheib U, et al. Among authors: hocker b. J Struct Biol. 2014 Feb;185(2):186-92. doi: 10.1016/j.jsb.2013.06.002. Epub 2013 Jun 17. J Struct Biol. 2014. PMID: 23792166

5

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy.

Huang PS, Feldmeier K, Parmeggiani F, Velasco DAF, Höcker B, Baker D. Huang PS, et al. Among authors: hocker b. Nat Chem Biol. 2016 Jan;12(1):29-34. doi: 10.1038/nchembio.1966. Epub 2015 Nov 23. Nat Chem Biol. 2016. PMID: 26595462 Free PMC article.

6

PocketOptimizer and the Design of Ligand Binding Sites.

Stiel AC, Nellen M, Höcker B. Stiel AC, et al. Among authors: hocker b. Methods Mol Biol. 2016;1414:63-75. doi: 10.1007/978-1-4939-3569-7_5. Methods Mol Biol. 2016. PMID: 27094286

7

Redesign of LAOBP to bind novel l-amino acid ligands.

Banda-Vázquez J, Shanmugaratnam S, Rodríguez-Sotres R, Torres-Larios A, Höcker B, Sosa-Peinado A. Banda-Vázquez J, et al. Among authors: hocker b. Protein Sci. 2018 May;27(5):957-968. doi: 10.1002/pro.3403. Epub 2018 Mar 22. Protein Sci. 2018. PMID: 29524280 Free PMC article.

8

Strategies for designing non-natural enzymes and binders.

Lechner H, Ferruz N, Höcker B. Lechner H, et al. Among authors: hocker b. Curr Opin Chem Biol. 2018 Dec;47:67-76. doi: 10.1016/j.cbpa.2018.07.022. Epub 2018 Sep 22. Curr Opin Chem Biol. 2018. PMID: 30248579 Free article. Review.

9

Identification and Analysis of Natural Building Blocks for Evolution-Guided Fragment-Based Protein Design.

Ferruz N, Lobos F, Lemm D, Toledo-Patino S, Farías-Rico JA, Schmidt S, Höcker B. Ferruz N, et al. Among authors: hocker b. J Mol Biol. 2020 Jun 12;432(13):3898-3914. doi: 10.1016/j.jmb.2020.04.013. Epub 2020 Apr 21. J Mol Biol. 2020. PMID: 32330481 Free PMC article.

10

A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.

Kröger P, Shanmugaratnam S, Ferruz N, Schweimer K, Höcker B. Kröger P, et al. Among authors: hocker b. Structure. 2021 May 6;29(5):433-443.e4. doi: 10.1016/j.str.2020.12.005. Epub 2021 Jan 5. Structure. 2021. PMID: 33406388 Free article.

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