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The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.
Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein.
Velázquez-López I, Valdés-García G, Romero Romero S, Maya Martínez R, Leal-Cervantes AI, Costas M, Sánchez-López R, Amero C, Pastor N, Fernández Velasco DA. Velázquez-López I, et al. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1656-1666. doi: 10.1016/j.bbagen.2018.04.014. Epub 2018 Apr 15. Biochim Biophys Acta Gen Subj. 2018. PMID: 29669263
FRET-based analysis and molecular modeling of the human GPN-loop GTPases 1 and 3 heterodimer unveils a dominant-negative protein complex.
Cristóbal-Mondragón GR, Lara-Chacón B, Santiago Á, De-la-Rosa V, González-González R, Muñiz-Luna JA, Ladrón-de-Guevara E, Romero-Romero S, Rangel-Yescas GE, Fernández Velasco DA, Islas LD, Pastor N, Sánchez-Olea R, Calera MR. Cristóbal-Mondragón GR, et al. FEBS J. 2019 Dec;286(23):4797-4818. doi: 10.1111/febs.14996. Epub 2019 Jul 22. FEBS J. 2019. PMID: 31298811 Free article.
Evolution, folding, and design of TIM barrels and related proteins.
Romero-Romero S, Kordes S, Michel F, Höcker B. Romero-Romero S, et al. Curr Opin Struct Biol. 2021 Jun;68:94-104. doi: 10.1016/j.sbi.2020.12.007. Epub 2021 Jan 13. Curr Opin Struct Biol. 2021. PMID: 33453500 Free PMC article. Review.
27 results