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Page 1
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.
Mizuno S, Ikegami M, Koyama T, Sunami K, Ogata D, Kage H, Yanagaki M, Ikeuchi H, Ueno T, Tanikawa M, Oda K, Osuga Y, Mano H, Kohsaka S. Mizuno S, et al. Among authors: ikeuchi h. Mol Cancer Ther. 2023 Feb 1;22(2):227-239. doi: 10.1158/1535-7163.MCT-22-0302. Mol Cancer Ther. 2023. PMID: 36442478 Free PMC article.
Detection of Novel Tyrosine Kinase Fusion Genes as Potential Therapeutic Targets in Bone and Soft Tissue Sarcomas Using DNA/RNA-based Clinical Sequencing.
Hasegawa N, Hayashi T, Niizuma H, Kikuta K, Imanishi J, Endo M, Ikeuchi H, Sasa K, Sano K, Hirabayashi K, Takagi T, Ishijima M, Kato S, Kohsaka S, Saito T, Suehara Y. Hasegawa N, et al. Among authors: ikeuchi h. Clin Orthop Relat Res. 2024 Mar 1;482(3):549-563. doi: 10.1097/CORR.0000000000002901. Epub 2023 Nov 28. Clin Orthop Relat Res. 2024. PMID: 38014853
The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
Shirai Y, Ueno T, Kojima S, Ikeuchi H, Kitada R, Koyama T, Takahashi F, Takahashi K, Ichimura K, Yoshida A, Sugino H, Mano H, Narita Y, Takahashi M, Kohsaka S. Shirai Y, et al. Among authors: ikeuchi h. J Neurooncol. 2024 Mar;167(1):75-88. doi: 10.1007/s11060-024-04563-z. Epub 2024 Feb 16. J Neurooncol. 2024. PMID: 38363490 Free PMC article.
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
Kohsaka S, Yagishita S, Shirai Y, Matsuno Y, Ueno T, Kojima S, Ikeuchi H, Ikegami M, Kitada R, Yoshioka KI, Toshimitsu K, Tabata K, Yokoi A, Doi T, Yamamoto N, Owa T, Hamada A, Mano H. Kohsaka S, et al. Among authors: ikeuchi h. NPJ Precis Oncol. 2024 May 24;8(1):117. doi: 10.1038/s41698-024-00610-0. NPJ Precis Oncol. 2024. PMID: 38789724 Free PMC article.
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway.
Ikeuchi H, Matsuno Y, Kusumoto-Matsuo R, Kojima S, Ueno T, Ikegami M, Kitada R, Sumiyoshi-Okuma H, Kojima Y, Yonemori K, Yatabe Y, Takamochi K, Suzuki K, Yoshioka KI, Mano H, Kohsaka S. Ikeuchi H, et al. Oncogene. 2024 Oct;43(41):3037-3048. doi: 10.1038/s41388-024-03105-1. Epub 2024 Aug 3. Oncogene. 2024. PMID: 39095584
The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells.
Oguro-Igashira E, Murakami M, Mori R, Kuwahara R, Kihara T, Kohara M, Fujiwara M, Motooka D, Okuzaki D, Arase M, Toyota H, Peng S, Ogino T, Kitabatake Y, Morii E, Hirota S, Ikeuchi H, Umemoto E, Kumanogoh A, Takeda K. Oguro-Igashira E, et al. Among authors: ikeuchi h. Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2318767121. doi: 10.1073/pnas.2318767121. Epub 2024 Oct 21. Proc Natl Acad Sci U S A. 2024. PMID: 39432783
417 results