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The anti-cancer drug dabrafenib is not cardiotoxic and inhibits cardiac remodelling and fibrosis in a murine model of hypertension.
Meijles DN, Cull JJ, Cooper STE, Markou T, Hardyman MA, Fuller SJ, Alharbi HO, Haines ZHR, Alcantara-Alonso V, Glennon PE, Sheppard MN, Sugden PH, Clerk A. Meijles DN, et al. Among authors: clerk a. Clin Sci (Lond). 2021 Jul 30;135(14):1631-1647. doi: 10.1042/CS20210192. Clin Sci (Lond). 2021. PMID: 34296750 Free PMC article.
Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.
Bogoyevitch MA, Glennon PE, Andersson MB, Clerk A, Lazou A, Marshall CJ, Parker PJ, Sugden PH. Bogoyevitch MA, et al. Among authors: clerk a. J Biol Chem. 1994 Jan 14;269(2):1110-9. J Biol Chem. 1994. PMID: 7507104 Free article.
205 results