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Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells.
Beltzig L, Schwarzenbach C, Leukel P, Frauenknecht KBM, Sommer C, Tancredi A, Hegi ME, Christmann M, Kaina B. Beltzig L, et al. Among authors: schwarzenbach c. Cancers (Basel). 2022 Apr 29;14(9):2233. doi: 10.3390/cancers14092233. Cancers (Basel). 2022. PMID: 35565362 Free PMC article.
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.
Reich TR, Schwarzenbach C, Vilar JB, Unger S, Mühlhäusler F, Nikolova T, Poplawski A, Baymaz HI, Beli P, Christmann M, Tomicic MT. Reich TR, et al. Among authors: schwarzenbach c. Cell Mol Life Sci. 2021 Jul;78(14):5587-5604. doi: 10.1007/s00018-021-03864-0. Epub 2021 Jun 8. Cell Mol Life Sci. 2021. PMID: 34100981 Free PMC article.