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A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1.
Leysen S, Burnley RJ, Rodriguez E, Milroy LG, Soini L, Adamski CJ, Nitschke L, Davis R, Obsil T, Brunsveld L, Crabbe T, Zoghbi HY, Ottmann C, Davis JM. Leysen S, et al. Among authors: milroy lg. J Mol Biol. 2021 Sep 17;433(19):167174. doi: 10.1016/j.jmb.2021.167174. Epub 2021 Jul 21. J Mol Biol. 2021. PMID: 34302818 Free PMC article.
The renaissance of Ras.
Milroy LG, Ottmann C. Milroy LG, et al. ACS Chem Biol. 2014 Nov 21;9(11):2447-58. doi: 10.1021/cb500555h. Epub 2014 Sep 23. ACS Chem Biol. 2014. PMID: 25148694 Review.
Stabilizer-Guided Inhibition of Protein-Protein Interactions.
Milroy LG, Bartel M, Henen MA, Leysen S, Adriaans JM, Brunsveld L, Landrieu I, Ottmann C. Milroy LG, et al. Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15720-4. doi: 10.1002/anie.201507976. Epub 2015 Nov 5. Angew Chem Int Ed Engl. 2015. PMID: 26537010
Structural interface between LRRK2 and 14-3-3 protein.
Stevers LM, de Vries RM, Doveston RG, Milroy LG, Brunsveld L, Ottmann C. Stevers LM, et al. Among authors: milroy lg. Biochem J. 2017 Mar 23;474(7):1273-1287. doi: 10.1042/BCJ20161078. Biochem J. 2017. PMID: 28202711
Supramolecular Chemistry Targeting Proteins.
van Dun S, Ottmann C, Milroy LG, Brunsveld L. van Dun S, et al. Among authors: milroy lg. J Am Chem Soc. 2017 Oct 11;139(40):13960-13968. doi: 10.1021/jacs.7b01979. Epub 2017 Sep 28. J Am Chem Soc. 2017. PMID: 28926241 Free PMC article.
Modulators of protein-protein interactions.
Milroy LG, Grossmann TN, Hennig S, Brunsveld L, Ottmann C. Milroy LG, et al. Chem Rev. 2014 May 14;114(9):4695-748. doi: 10.1021/cr400698c. Epub 2014 Apr 15. Chem Rev. 2014. PMID: 24735440 Review. No abstract available.
A natural-product switch for a dynamic protein interface.
Scheepstra M, Nieto L, Hirsch AK, Fuchs S, Leysen S, Lam CV, in het Panhuis L, van Boeckel CA, Wienk H, Boelens R, Ottmann C, Milroy LG, Brunsveld L. Scheepstra M, et al. Among authors: milroy lg. Angew Chem Int Ed Engl. 2014 Jun 16;53(25):6443-8. doi: 10.1002/anie.201403773. Epub 2014 May 12. Angew Chem Int Ed Engl. 2014. PMID: 24821627
51 results