Zhang T - Search Results

1

H₂dpa derivatives containing pentadentate ligands: An acyclic adjuvant potentiates meropenem activity in vitro and in vivo against metallo-β-lactamase-producing Enterobacterales.

Chen F, Bai M, Liu W, Kong H, Zhang T, Yao H, Zhang E, Du J, Qin S. Chen F, et al. Among authors: zhang t, zhang e. Eur J Med Chem. 2021 Nov 15;224:113702. doi: 10.1016/j.ejmech.2021.113702. Epub 2021 Jul 13. Eur J Med Chem. 2021. PMID: 34303873

2

Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives.

Bi Y, Yang X, Zhang T, Liu Z, Zhang X, Lu J, Cheng K, Xu J, Wang H, Lv G, Lewis PJ, Meng Q, Ma C. Bi Y, et al. Among authors: zhang t, zhang x. Eur J Med Chem. 2015 Aug 28;101:71-80. doi: 10.1016/j.ejmech.2015.06.021. Epub 2015 Jun 17. Eur J Med Chem. 2015. PMID: 26114813

3

Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety.

Zhang T, Shen W, Liu M, Zhang R, Wang M, Li L, Wang B, Guo H, Lu Y. Zhang T, et al. Among authors: zhang r. Eur J Med Chem. 2015 Nov 2;104:73-85. doi: 10.1016/j.ejmech.2015.09.030. Epub 2015 Sep 30. Eur J Med Chem. 2015. PMID: 26435513

4

Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.

Hou J, Wan S, Wang G, Zhang T, Li Z, Tian Y, Yu Y, Wu X, Zhang J. Hou J, et al. Among authors: zhang t, zhang j. Eur J Med Chem. 2016 Aug 8;118:276-89. doi: 10.1016/j.ejmech.2016.04.026. Epub 2016 Apr 20. Eur J Med Chem. 2016. PMID: 27132165

5

Design, synthesis, biological evaluation and molecular modeling of novel 2-amino-4-(1-phenylethoxy) pyridine derivatives as potential ROS1 inhibitors.

Tian Y, Zhang T, Long L, Li Z, Wan S, Wang G, Yu Y, Hou J, Wu X, Zhang J. Tian Y, et al. Among authors: zhang t, zhang j. Eur J Med Chem. 2018 Jan 1;143:182-199. doi: 10.1016/j.ejmech.2017.11.002. Epub 2017 Nov 3. Eur J Med Chem. 2018. PMID: 29174814

6

Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.

Li P, Wang B, Zhang X, Batt SM, Besra GS, Zhang T, Ma C, Zhang D, Lin Z, Li G, Huang H, Lu Y. Li P, et al. Among authors: zhang t, zhang d, zhang x. Eur J Med Chem. 2018 Dec 5;160:157-170. doi: 10.1016/j.ejmech.2018.09.042. Epub 2018 Sep 17. Eur J Med Chem. 2018. PMID: 30336450

7

Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors.

Liu S, Jiang Y, Yan R, Li Z, Wan S, Zhang T, Wu X, Hou J, Zhu Z, Tian Y, Zhang J. Liu S, et al. Among authors: zhang t, zhang j. Eur J Med Chem. 2019 Oct 1;179:358-375. doi: 10.1016/j.ejmech.2019.06.043. Epub 2019 Jun 25. Eur J Med Chem. 2019. PMID: 31260890

8

Design, synthesis and biological evaluation of 2-amino-4-(1,2,4-triazol)pyridine derivatives as potent EGFR inhibitors to overcome TKI-resistance.

Yang H, Yan R, Jiang Y, Yang Z, Zhang X, Zhou M, Wu X, Zhang T, Zhang J. Yang H, et al. Among authors: zhang t, zhang j, zhang x. Eur J Med Chem. 2020 Feb 1;187:111966. doi: 10.1016/j.ejmech.2019.111966. Epub 2019 Dec 14. Eur J Med Chem. 2020. PMID: 31869655 Review.

9

Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification.

Wang Y, He X, Li C, Ma Y, Xue W, Hu B, Wang J, Zhang T, Zhang F. Wang Y, et al. Among authors: zhang f, zhang t. Eur J Med Chem. 2020 May 1;193:112235. doi: 10.1016/j.ejmech.2020.112235. Epub 2020 Mar 16. Eur J Med Chem. 2020. PMID: 32203789

10

Design, synthesis and inhibitory activity of novel 2, 3-dihydroquinolin-4(1H)-one derivatives as potential succinate dehydrogenase inhibitors.

Cheng W, Yan Y, Xiao T, Zhang G, Zhang T, Lu T, Jiang W, Wang J, Tang X. Cheng W, et al. Among authors: zhang g, zhang t. Eur J Med Chem. 2021 Mar 15;214:113246. doi: 10.1016/j.ejmech.2021.113246. Epub 2021 Feb 2. Eur J Med Chem. 2021. PMID: 33582385

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