Allegra CJ - Search Results

1

Antifolate metabolism and sites of action: implications for the design of new antifolates.

Fitzhugh AL, Chabner BA, Sholar PW, Baram J, Allegra CJ. Fitzhugh AL, et al. Among authors: allegra cj. NCI Monogr. 1987;(5):153-7. NCI Monogr. 1987. PMID: 3431590

2

Preliminary results of a phase II trial for the treatment of metastatic breast cancer with 5-fluorouracil and leucovorin.

Allegra CJ, Chabner BA, Sholar PW, Bagley C, Drake JC, Lippman ME. Allegra CJ, et al. NCI Monogr. 1987;(5):199-202. NCI Monogr. 1987. PMID: 3501543

3

Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue.

Johnston PG, Liang CM, Henry S, Chabner BA, Allegra CJ. Johnston PG, et al. Among authors: allegra cj. Cancer Res. 1991 Dec 15;51(24):6668-76. Cancer Res. 1991. PMID: 1720706

4

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.

Chu E, Koeller DM, Casey JL, Drake JC, Chabner BA, Elwood PC, Zinn S, Allegra CJ. Chu E, et al. Among authors: allegra cj. Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):8977-81. doi: 10.1073/pnas.88.20.8977. Proc Natl Acad Sci U S A. 1991. PMID: 1924359 Free PMC article.

5

Mechanism of leucovorin reversal of methotrexate cytotoxicity in human MCF-7 breast cancer cells.

Boarman DM, Baram J, Allegra CJ. Boarman DM, et al. Among authors: allegra cj. Biochem Pharmacol. 1990 Dec 15;40(12):2651-60. doi: 10.1016/0006-2952(90)90583-7. Biochem Pharmacol. 1990. PMID: 2260989

6

Inhibition of folate-dependent enzymes by 7-OH-methotrexate.

Sholar PW, Baram J, Seither R, Allegra CJ. Sholar PW, et al. Among authors: allegra cj. Biochem Pharmacol. 1988 Sep 15;37(18):3531-4. doi: 10.1016/0006-2952(88)90709-5. Biochem Pharmacol. 1988. PMID: 2458733 No abstract available.

7

Identification and biochemical properties of 10-formyldihydrofolate, a novel folate found in methotrexate-treated cells.

Baram J, Chabner BA, Drake JC, Fitzhugh AL, Sholar PW, Allegra CJ. Baram J, et al. Among authors: allegra cj. J Biol Chem. 1988 May 25;263(15):7105-11. J Biol Chem. 1988. PMID: 3366769 Free article.

8

Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells.

Drake JC, Baram J, Allegra CJ. Drake JC, et al. Among authors: allegra cj. Biochem Pharmacol. 1990 Feb 1;39(3):615-8. doi: 10.1016/0006-2952(90)90073-t. Biochem Pharmacol. 1990. PMID: 2306274 No abstract available.

9

Mechanism of thymidylate synthase inhibition by methotrexate in human neoplastic cell lines and normal human myeloid progenitor cells.

Chu E, Drake JC, Boarman D, Baram J, Allegra CJ. Chu E, et al. Among authors: allegra cj. J Biol Chem. 1990 May 25;265(15):8470-8. J Biol Chem. 1990. PMID: 2341391 Free article.

10

Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.

Allegra CJ, Hoang K, Yeh GC, Drake JC, Baram J. Allegra CJ, et al. J Biol Chem. 1987 Oct 5;262(28):13520-6. J Biol Chem. 1987. PMID: 2443493 Free article.

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