Gutkind JS - Search Results

1

Calcium signaling induces a partial EMT.

Norgard RJ, Pitarresi JR, Maddipati R, Aiello-Couzo NM, Balli D, Li J, Yamazoe T, Wengyn MD, Millstein ID, Folkert IW, Rosario-Berrios DN, Kim IK, Bassett JB, Payne R, Berry CT, Feng X, Sun K, Cioffi M, Chakraborty P, Jolly MK, Gutkind JS, Lyden D, Freedman BD, Foskett JK, Rustgi AK, Stanger BZ. Norgard RJ, et al. Among authors: gutkind js. EMBO Rep. 2021 Sep 6;22(9):e51872. doi: 10.15252/embr.202051872. Epub 2021 Jul 29. EMBO Rep. 2021. PMID: 34324787 Free PMC article.

2

Oncotargeting G proteins: The Hippo in the room.

Feng X, Chen Q, Gutkind JS. Feng X, et al. Among authors: gutkind js. Oncotarget. 2014 Nov 30;5(22):10997-9. doi: 10.18632/oncotarget.2815. Oncotarget. 2014. PMID: 25526026 Free PMC article.

3

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis.

Goto Y, Ando T, Izumi H, Feng X, Arang N, Gilardi M, Wang Z, Ando K, Gutkind JS. Goto Y, et al. Among authors: gutkind js. Oncogene. 2020 May;39(20):4014-4027. doi: 10.1038/s41388-020-1272-x. Epub 2020 Mar 23. Oncogene. 2020. PMID: 32205868 Free PMC article.

4

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1.

Ando T, Arang N, Wang Z, Costea DE, Feng X, Goto Y, Izumi H, Gilardi M, Ando K, Gutkind JS. Ando T, et al. Among authors: gutkind js. Commun Biol. 2021 Nov 1;4(1):1237. doi: 10.1038/s42003-021-02744-4. Commun Biol. 2021. PMID: 34725466 Free PMC article.

5

YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution.

Faraji F, Ramirez SI, Clubb LM, Sato K, Burghi V, Hoang TS, Officer A, Anguiano Quiroz PY, Galloway WMG, Mikulski Z, Medetgul-Ernar K, Marangoni P, Jones KB, Cao Y, Molinolo AA, Kim K, Sakaguchi K, Califano JA 3rd, Smith Q, Goren A, Klein OD, Tamayo P, Gutkind JS. Faraji F, et al. Among authors: gutkind js. Nat Commun. 2025 Jan 8;16(1):498. doi: 10.1038/s41467-024-55660-6. Nat Commun. 2025. PMID: 39779672 Free PMC article.

6

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS. Feng X, et al. Among authors: gutkind js. Cancer Cell. 2014 Jun 16;25(6):831-45. doi: 10.1016/j.ccr.2014.04.016. Epub 2014 May 29. Cancer Cell. 2014. PMID: 24882515 Free PMC article.

7

Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.

Iglesias-Bartolome R, Torres D, Marone R, Feng X, Martin D, Simaan M, Chen M, Weinstein LS, Taylor SS, Molinolo AA, Gutkind JS. Iglesias-Bartolome R, et al. Among authors: gutkind js. Nat Cell Biol. 2015 Jun;17(6):793-803. doi: 10.1038/ncb3164. Epub 2015 May 11. Nat Cell Biol. 2015. PMID: 25961504 Free PMC article.

8

Genetic evidence that β-arrestins are dispensable for the initiation of β₂-adrenergic receptor signaling to ERK.

O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. O'Hayre M, et al. Among authors: gutkind js. Sci Signal. 2017 Jun 20;10(484):eaal3395. doi: 10.1126/scisignal.aal3395. Sci Signal. 2017. PMID: 28634209 Free PMC article.

9

The NOTCH4-HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.

Fukusumi T, Guo TW, Sakai A, Ando M, Ren S, Haft S, Liu C, Amornphimoltham P, Gutkind JS, Califano JA. Fukusumi T, et al. Among authors: gutkind js. Clin Cancer Res. 2018 Feb 1;24(3):619-633. doi: 10.1158/1078-0432.CCR-17-1366. Epub 2017 Nov 16. Clin Cancer Res. 2018. PMID: 29146722 Free PMC article.

10

Metformin Inhibits Progression of Head and Neck Squamous Cell Carcinoma by Acting Directly on Carcinoma-Initiating Cells.

Wu X, Yeerna H, Goto Y, Ando T, Wu VH, Zhang X, Wang Z, Amornphimoltham P, Murphy AN, Tamayo P, Chen Q, Lippman SM, Gutkind JS. Wu X, et al. Among authors: gutkind js. Cancer Res. 2019 Sep 1;79(17):4360-4370. doi: 10.1158/0008-5472.CAN-18-3525. Epub 2019 Jul 10. Cancer Res. 2019. PMID: 31292160 Free PMC article.

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