Hindley CJ - Search Results

1

ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK.

Munck JM, Berdini V, Bevan L, Brothwood JL, Castro J, Courtin A, East C, Ferraldeschi R, Heightman TD, Hindley CJ, Kucia-Tran J, Lyons JF, Martins V, Muench S, Murray CW, Norton D, O'Reilly M, Reader M, Rees DC, Rich SJ, Richardson CJ, Shah AD, Stanczuk L, Thompson NT, Wilsher NE, Woolford AJ, Wallis NG. Munck JM, et al. Among authors: hindley cj. Mol Cancer Ther. 2021 Oct;20(10):1757-1768. doi: 10.1158/1535-7163.MCT-20-0909. Epub 2021 Jul 30. Mol Cancer Ther. 2021. PMID: 34330842

2

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis.

Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A. Ali F, et al. Development. 2011 Oct;138(19):4267-77. doi: 10.1242/dev.067900. Epub 2011 Aug 18. Development. 2011. PMID: 21852393 Free PMC article.

3

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.

Hindley C, Ali F, McDowell G, Cheng K, Jones A, Guillemot F, Philpott A. Hindley C, et al. Development. 2012 May;139(10):1718-23. doi: 10.1242/dev.077552. Epub 2012 Apr 4. Development. 2012. PMID: 22491944 Free PMC article.

4

Co-ordination of cell cycle and differentiation in the developing nervous system.

Hindley C, Philpott A. Hindley C, et al. Biochem J. 2012 Jun 15;444(3):375-82. doi: 10.1042/BJ20112040. Biochem J. 2012. PMID: 22642576 Free PMC article. Review.

5

Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A. Azzarelli R, et al. Dev Cell. 2017 May 8;41(3):274-286.e5. doi: 10.1016/j.devcel.2017.04.004. Epub 2017 Apr 27. Dev Cell. 2017. PMID: 28457793 Free PMC article.

6

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.

McDowell GS, Hindley CJ, Lippens G, Landrieu I, Philpott A. McDowell GS, et al. Among authors: hindley cj. BMC Biochem. 2014 Nov 6;15:24. doi: 10.1186/s12858-014-0024-3. BMC Biochem. 2014. PMID: 25374254 Free PMC article.

7

The cell cycle and pluripotency.

Hindley C, Philpott A. Hindley C, et al. Biochem J. 2013 Apr 15;451(2):135-43. doi: 10.1042/BJ20121627. Biochem J. 2013. PMID: 23535166 Free PMC article. Review.

8

Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysis.

Vosper JM, McDowell GS, Hindley CJ, Fiore-Heriche CS, Kucerova R, Horan I, Philpott A. Vosper JM, et al. Among authors: hindley cj. J Biol Chem. 2009 Jun 5;284(23):15458-68. doi: 10.1074/jbc.M809366200. Epub 2009 Mar 31. J Biol Chem. 2009. PMID: 19336407 Free PMC article.

9

The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis.

Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A. Almeida AD, et al. Among authors: hindley cj. Neural Dev. 2010 Jan 4;5:1. doi: 10.1186/1749-8104-5-1. Neural Dev. 2010. PMID: 20047651 Free PMC article.

10

Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases.

Hindley CJ, McDowell GS, Wise H, Philpott A. Hindley CJ, et al. Int J Dev Biol. 2011;55(3):249-60. doi: 10.1387/ijdb.103171ch. Int J Dev Biol. 2011. PMID: 21710433 Free article. Review.

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