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Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients.
Rouchka EC, Chariker JH, Alejandro B, Adcock RS, Singhal R, Ramirez J, Palmer KE, Lasnik AB, Carrico R, Arnold FW, Furmanek S, Zhang M, Wolf LA, Waigel S, Zacharias W, Bordon J, Chung D. Rouchka EC, et al. Among authors: chung d. Sci Rep. 2021 Aug 3;11(1):15715. doi: 10.1038/s41598-021-95197-y. Sci Rep. 2021. PMID: 34344959 Free PMC article.
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.
Chung DH, Golden JE, Adcock RS, Schroeder CE, Chu YK, Sotsky JB, Cramer DE, Chilton PM, Song C, Anantpadma M, Davey RA, Prodhan AI, Yin X, Zhang X. Chung DH, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4552-62. doi: 10.1128/AAC.00282-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27185801 Free PMC article.
Variant analysis of 1,040 SARS-CoV-2 genomes.
Rouchka EC, Chariker JH, Chung D. Rouchka EC, et al. Among authors: chung d. PLoS One. 2020 Nov 5;15(11):e0241535. doi: 10.1371/journal.pone.0241535. eCollection 2020. PLoS One. 2020. PMID: 33152019 Free PMC article.
3,501 results