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Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodies.
Stefan MA, Light YK, Schwedler JL, McIlroy PR, Courtney CM, Saada EA, Thatcher CE, Phillips AM, Bourguet FA, Mageeney CM, McCloy SA, Collette NM, Negrete OA, Schoeniger JS, Weilhammer DR, Harmon B. Stefan MA, et al. Among authors: mcilroy pr. MAbs. 2021 Jan-Dec;13(1):1958663. doi: 10.1080/19420862.2021.1958663. MAbs. 2021. PMID: 34348076 Free PMC article.
Computationally restoring the potency of a clinical antibody against Omicron.
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW; Tri-lab COVID-19 Consortium; Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM. Desautels TA, et al. Nature. 2024 May;629(8013):878-885. doi: 10.1038/s41586-024-07385-1. Epub 2024 May 8. Nature. 2024. PMID: 38720086 Free PMC article.