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Page 1
Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro.
Mellis IA, Edelstein HI, Truitt R, Goyal Y, Beck LE, Symmons O, Dunagin MC, Linares Saldana RA, Shah PP, Pérez-Bermejo JA, Padmanabhan A, Yang W, Jain R, Raj A. Mellis IA, et al. Among authors: edelstein hi. Cell Syst. 2021 Sep 22;12(9):885-899.e8. doi: 10.1016/j.cels.2021.07.003. Epub 2021 Aug 4. Cell Syst. 2021. PMID: 34352221 Free PMC article.
Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.
Liu Y, Conlon DM, Bi X, Slovik KJ, Shi J, Edelstein HI, Millar JS, Javaheri A, Cuchel M, Pashos EE, Iqbal J, Hussain MM, Hegele RA, Yang W, Duncan SA, Rader DJ, Morrisey EE. Liu Y, et al. Among authors: edelstein hi. Cell Rep. 2017 May 16;19(7):1456-1466. doi: 10.1016/j.celrep.2017.04.064. Cell Rep. 2017. PMID: 28514664 Free PMC article.
The sound of silence: Transgene silencing in mammalian cell engineering.
Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, Khalil AS, Wong WW, Collins JJ, Rosser SJ, Polizzi K, Elowitz MB, Fussenegger M, Hilton IB, Leonard JN, Bintu L, Galloway KE, Deans TL. Cabrera A, et al. Among authors: edelstein hi. Cell Syst. 2022 Dec 21;13(12):950-973. doi: 10.1016/j.cels.2022.11.005. Cell Syst. 2022. PMID: 36549273 Free PMC article. Review.
Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues.
Paek J, Park SE, Lu Q, Park KT, Cho M, Oh JM, Kwon KW, Yi YS, Song JW, Edelstein HI, Ishibashi J, Yang W, Myerson JW, Kiseleva RY, Aprelev P, Hood ED, Stambolian D, Seale P, Muzykantov VR, Huh D. Paek J, et al. Among authors: edelstein hi. ACS Nano. 2019 Jul 23;13(7):7627-7643. doi: 10.1021/acsnano.9b00686. Epub 2019 Jun 18. ACS Nano. 2019. PMID: 31194909
The evolution of synthetic receptor systems.
Manhas J, Edelstein HI, Leonard JN, Morsut L. Manhas J, et al. Among authors: edelstein hi. Nat Chem Biol. 2022 Mar;18(3):244-255. doi: 10.1038/s41589-021-00926-z. Epub 2022 Jan 20. Nat Chem Biol. 2022. PMID: 35058646 Free PMC article. Review.
Control of mammalian cell-based devices with genetic programming.
Dray KE, Edelstein HI, Dreyer KS, Leonard JN. Dray KE, et al. Among authors: edelstein hi. Curr Opin Syst Biol. 2021 Dec;28:100372. doi: 10.1016/j.coisb.2021.100372. Epub 2021 Aug 14. Curr Opin Syst Biol. 2021. PMID: 34527830 Free PMC article.
Elucidation and refinement of synthetic receptor mechanisms.
Edelstein HI, Donahue PS, Muldoon JJ, Kang AK, Dolberg TB, Battaglia LM, Allchin ER, Hong M, Leonard JN. Edelstein HI, et al. Synth Biol (Oxf). 2020 Sep 30;5(1):ysaa017. doi: 10.1093/synbio/ysaa017. eCollection 2020. Synth Biol (Oxf). 2020. PMID: 33392392 Free PMC article.