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Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
Jan A, Jansonius B, Delaidelli A, Bhanshali F, An YA, Ferreira N, Smits LM, Negri GL, Schwamborn JC, Jensen PH, Mackenzie IR, Taubert S, Sorensen PH. Jan A, et al. Acta Neuropathol Commun. 2018 Jul 2;6(1):54. doi: 10.1186/s40478-018-0554-9. Acta Neuropathol Commun. 2018. PMID: 29961428 Free PMC article.
α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.
Delaidelli A, Richner M, Jiang L, van der Laan A, Bergholdt Jul Christiansen I, Ferreira N, Nyengaard JR, Vægter CB, Jensen PH, Mackenzie IR, Sorensen PH, Jan A. Delaidelli A, et al. Among authors: jan a. Acta Neuropathol Commun. 2021 Jun 6;9(1):105. doi: 10.1186/s40478-021-01209-3. Acta Neuropathol Commun. 2021. PMID: 34092244 Free PMC article.
Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy.
Ferreira N, Richner M, van der Laan A, Bergholdt Jul Christiansen I, Vægter CB, Nyengaard JR, Halliday GM, Weiss J, Giasson BI, Mackenzie IR, Jensen PH, Jan A. Ferreira N, et al. Among authors: jan a. Brain Commun. 2021 May 14;3(2):fcab104. doi: 10.1093/braincomms/fcab104. eCollection 2021. Brain Commun. 2021. PMID: 34136810 Free PMC article.
Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion.
Richner M, Gonçalves NP, Jensen PH, Nyengaard JR, Vægter CB, Jan A. Richner M, et al. Among authors: jan a. STAR Protoc. 2022 Feb 17;3(1):101181. doi: 10.1016/j.xpro.2022.101181. eCollection 2022 Mar 18. STAR Protoc. 2022. PMID: 35243373 Free PMC article.
This protocol outlines a minimally invasive and quickly performed approach for transgene delivery in the extracranial nervous system of adult mice using recombinant adeno-associated virus (AAV). ...For complete details on the use and execution of this protocol, please refe …
This protocol outlines a minimally invasive and quickly performed approach for transgene delivery in the extracranial nervous system …
Correction to: Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy.
Ferreira N, Richner M, van der Laan A, Jul Christiansen IB, Vægter CB, Nyengaard JR, Halliday GM, Weis J, Giasson BI, Mackenzie IR, Jensen PH, Jan A. Ferreira N, et al. Among authors: jan a. Brain Commun. 2022 Apr 4;4(2):fcac067. doi: 10.1093/braincomms/fcac067. eCollection 2022. Brain Commun. 2022. PMID: 35386219 Free PMC article.
492 results