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Pharmacological Targeting of BMP6-SMAD Mediated Hepcidin Expression Does Not Improve the Outcome of Systemic Infections With Intra-Or Extracellular Gram-Negative Bacteria in Mice.
Hoffmann A, de Souza LV, Seifert M, von Raffay L, Haschka D, Grubwieser P, Grander M, Mitterstiller AM, Nairz M, Poli M, Weiss G. Hoffmann A, et al. Among authors: haschka d. Front Cell Infect Microbiol. 2021 Jul 23;11:705087. doi: 10.3389/fcimb.2021.705087. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34368018 Free PMC article.
Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB.
Sonnweber T, Nachbaur D, Schroll A, Nairz M, Seifert M, Demetz E, Haschka D, Mitterstiller AM, Kleinsasser A, Burtscher M, Trübsbach S, Murphy AT, Wroblewski V, Witcher DR, Mleczko-Sanecka K, Vecchi C, Muckenthaler MU, Pietrangelo A, Theurl I, Weiss G. Sonnweber T, et al. Among authors: haschka d. Gut. 2014 Dec;63(12):1951-9. doi: 10.1136/gutjnl-2013-305317. Epub 2014 Mar 5. Gut. 2014. PMID: 24598129 Free article.
Iron at the interface of immunity and infection.
Nairz M, Haschka D, Demetz E, Weiss G. Nairz M, et al. Among authors: haschka d. Front Pharmacol. 2014 Jul 16;5:152. doi: 10.3389/fphar.2014.00152. eCollection 2014. Front Pharmacol. 2014. PMID: 25076907 Free PMC article. Review.
Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.
Asshoff M, Petzer V, Warr MR, Haschka D, Tymoszuk P, Demetz E, Seifert M, Posch W, Nairz M, Maciejewski P, Fowles P, Burns CJ, Smith G, Wagner KU, Weiss G, Whitney JA, Theurl I. Asshoff M, et al. Among authors: haschka d. Blood. 2017 Mar 30;129(13):1823-1830. doi: 10.1182/blood-2016-09-740092. Epub 2017 Feb 10. Blood. 2017. PMID: 28188131 Free PMC article.
Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice.
Nairz M, Metzendorf C, Vujic-Spasic M, Mitterstiller AM, Schroll A, Haschka D, Hoffmann A, Von Raffay L, Sparla R, Huck CW, Talasz H, Moser PL, Muckenthaler MU, Weiss G. Nairz M, et al. Among authors: haschka d. Haematologica. 2021 Dec 1;106(12):3149-3161. doi: 10.3324/haematol.2019.241745. Haematologica. 2021. PMID: 33054105 Free PMC article.
47 results