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Antiplatelet drugs block platelet activation by VITT patient serum.
Smith CW, Montague SJ, Kardeby C, Di Y, Lowe GC, Lester WA, Watson SP, Nicolson PLR. Smith CW, et al. Among authors: nicolson plr. Blood. 2021 Dec 23;138(25):2733-2740. doi: 10.1182/blood.2021012277. Blood. 2021. PMID: 34375398 Free PMC article. No abstract available.
Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI.
Nicolson PLR, Hughes CE, Watson S, Nock SH, Hardy AT, Watson CN, Montague SJ, Clifford H, Huissoon AP, Malcor JD, Thomas MR, Pollitt AY, Tomlinson MG, Pratt G, Watson SP. Nicolson PLR, et al. Haematologica. 2018 Dec;103(12):2097-2108. doi: 10.3324/haematol.2018.193391. Epub 2018 Jul 19. Haematologica. 2018. PMID: 30026342 Free PMC article.
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
Real-world experience with caplacizumab in the management of acute TTP.
Dutt T, Shaw RJ, Stubbs M, Yong J, Bailiff B, Cranfield T, Crowley MP, Desborough M, Eyre TA, Gooding R, Grainger J, Hanley J, Haughton J, Hermans J, Hill Q, Humphrey L, Lowe G, Lyall H, Mohsin M, Nicolson PLR, Priddee N, Rampotas A, Rayment R, Rhodes S, Taylor A, Thomas W, Tomkins O, Van Veen JJ, Lane S, Toh CH, Scully M. Dutt T, et al. Among authors: nicolson plr. Blood. 2021 Apr 1;137(13):1731-1740. doi: 10.1182/blood.2020007599. Blood. 2021. PMID: 33150355 Free article.
Antiprothrombin antibodies induce platelet activation: A possible explanation for anti-FXa therapy failure in patients with antiphospholipid syndrome?
Chayoua W, Nicolson PLR, Meijers JCM, Kardeby C, Garcia-Quintanilla L, Devreese KMJ, de Laat B, Watson SP, de Groot PG. Chayoua W, et al. Among authors: nicolson plr. J Thromb Haemost. 2021 Jul;19(7):1776-1782. doi: 10.1111/jth.15320. Epub 2021 May 5. J Thromb Haemost. 2021. PMID: 33774918 Free PMC article.
46 results