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Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy.
Warnecke N, Ulmer BM, Laufer SD, Shibamiya A, Krämer E, Neuber C, Hanke S, Behrens C, Loos M, Münch J, Kühnisch J, Klaassen S, Eschenhagen T, Patten-Hamel M, Carrier L, Mearini G. Warnecke N, et al. Among authors: kramer e. Stem Cell Res. 2021 Aug;55:102489. doi: 10.1016/j.scr.2021.102489. Epub 2021 Aug 5. Stem Cell Res. 2021. PMID: 34375846 Free article.
A new polymorphism in human calmodulin III gene promoter is a potential modifier gene for familial hypertrophic cardiomyopathy.
Friedrich FW, Bausero P, Sun Y, Treszl A, Krämer E, Juhr D, Richard P, Wegscheider K, Schwartz K, Brito D, Arbustini E, Waldenström A, Isnard R, Komajda M, Eschenhagen T, Carrier L; EUROGENE Heart Failure Project. Friedrich FW, et al. Among authors: kramer e. Eur Heart J. 2009 Jul;30(13):1648-55. doi: 10.1093/eurheartj/ehp153. Epub 2009 May 8. Eur Heart J. 2009. PMID: 19429631
Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Vignier N, Schlossarek S, Fraysse B, Mearini G, Krämer E, Pointu H, Mougenot N, Guiard J, Reimer R, Hohenberg H, Schwartz K, Vernet M, Eschenhagen T, Carrier L. Vignier N, et al. Among authors: kramer e. Circ Res. 2009 Jul 31;105(3):239-48. doi: 10.1161/CIRCRESAHA.109.201251. Epub 2009 Jul 9. Circ Res. 2009. PMID: 19590044
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L. Mearini G, et al. Among authors: kramer e. Cardiovasc Res. 2010 Jan 15;85(2):357-66. doi: 10.1093/cvr/cvp348. Epub 2009 Oct 22. Cardiovasc Res. 2010. PMID: 19850579 Free PMC article.
Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice.
Fraysse B, Weinberger F, Bardswell SC, Cuello F, Vignier N, Geertz B, Starbatty J, Krämer E, Coirault C, Eschenhagen T, Kentish JC, Avkiran M, Carrier L. Fraysse B, et al. Among authors: kramer e. J Mol Cell Cardiol. 2012 Jun;52(6):1299-307. doi: 10.1016/j.yjmcc.2012.03.009. Epub 2012 Mar 23. J Mol Cell Cardiol. 2012. PMID: 22465693 Free PMC article.
BSE-associated prion-amyloid cardiomyopathy in primates.
Krasemann S, Mearini G, Krämer E, Wagenführ K, Schulz-Schaeffer W, Neumann M, Bodemer W, Kaup FJ, Beekes M, Carrier L, Aguzzi A, Glatzel M. Krasemann S, et al. Among authors: kramer e. Emerg Infect Dis. 2013 Jun;19(6):985-8. doi: 10.3201/eid1906.120906. Emerg Infect Dis. 2013. PMID: 23735198 Free PMC article.
Repair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy.
Mearini G, Stimpel D, Krämer E, Geertz B, Braren I, Gedicke-Hornung C, Précigout G, Müller OJ, Katus HA, Eschenhagen T, Voit T, Garcia L, Lorain S, Carrier L. Mearini G, et al. Among authors: kramer e. Mol Ther Nucleic Acids. 2013 Jul 2;2(7):e102. doi: 10.1038/mtna.2013.31. Mol Ther Nucleic Acids. 2013. PMID: 23820890 Free PMC article.
837 results