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Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.
Jung S, Fuchs N, Johe P, Wagner A, Diehl E, Yuliani T, Zimmer C, Barthels F, Zimmermann RA, Klein P, Waigel W, Meyr J, Opatz T, Tenzer S, Distler U, Räder HJ, Kersten C, Engels B, Hellmich UA, Klein J, Schirmeister T. Jung S, et al. Among authors: rader hj. J Med Chem. 2021 Aug 26;64(16):12322-12358. doi: 10.1021/acs.jmedchem.1c01002. Epub 2021 Aug 11. J Med Chem. 2021. PMID: 34378914
pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages.
Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A, Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ, Tenzer S, Marini F, Schuppan D, Nuhn L. Kaps L, et al. Among authors: rader hj. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2122310119. doi: 10.1073/pnas.2122310119. Epub 2022 Mar 15. Proc Natl Acad Sci U S A. 2022. PMID: 35290110 Free PMC article.
Self-Immolative RAFT-Polymer End Group Modification.
Scherger M, Räder HJ, Nuhn L. Scherger M, et al. Among authors: rader hj. Macromol Rapid Commun. 2021 Apr;42(8):e2000752. doi: 10.1002/marc.202000752. Epub 2021 Feb 25. Macromol Rapid Commun. 2021. PMID: 33629782
Targeted Repolarization of Tumor-Associated Macrophages via Imidazoquinoline-Linked Nanobodies.
Bolli E, Scherger M, Arnouk SM, Pombo Antunes AR, Straßburger D, Urschbach M, Stickdorn J, De Vlaminck K, Movahedi K, Räder HJ, Hernot S, Besenius P, Van Ginderachter JA, Nuhn L. Bolli E, et al. Among authors: rader hj. Adv Sci (Weinh). 2021 Mar 8;8(10):2004574. doi: 10.1002/advs.202004574. eCollection 2021 May. Adv Sci (Weinh). 2021. PMID: 34026453 Free PMC article.
47 results