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Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses.
Grazia Martina M, Vicenti I, Bauer L, Crespan E, Rango E, Boccuto A, Olivieri N, Incerti M, Zwaagstra M, Allodi M, Bertoni S, Dreassi E, Zazzi M, van Kuppeveld FJM, Maga G, Radi M. Grazia Martina M, et al. Among authors: incerti m. ChemMedChem. 2021 Dec 6;16(23):3548-3552. doi: 10.1002/cmdc.202100483. Epub 2021 Sep 7. ChemMedChem. 2021. PMID: 34382337 Free PMC article.
Structure-activity relationships and mechanism of action of Eph-ephrin antagonists: interaction of cholanic acid with the EphA2 receptor.
Tognolini M, Incerti M, Hassan-Mohamed I, Giorgio C, Russo S, Bruni R, Lelli B, Bracci L, Noberini R, Pasquale EB, Barocelli E, Vicini P, Mor M, Lodola A. Tognolini M, et al. Among authors: incerti m. ChemMedChem. 2012 Jun;7(6):1071-83. doi: 10.1002/cmdc.201200102. Epub 2012 Apr 23. ChemMedChem. 2012. PMID: 22529030 Free PMC article.
Δ(5)-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system.
Castelli R, Tognolini M, Vacondio F, Incerti M, Pala D, Callegari D, Bertoni S, Giorgio C, Hassan-Mohamed I, Zanotti I, Bugatti A, Rusnati M, Festuccia C, Rivara S, Barocelli E, Mor M, Lodola A. Castelli R, et al. Among authors: incerti m. Eur J Med Chem. 2015 Oct 20;103:312-24. doi: 10.1016/j.ejmech.2015.08.048. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26363867
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice.
Giorgio C, Incerti M, Pala D, Russo S, Chiodelli P, Rusnati M, Cantoni AM, Di Lecce R, Barocelli E, Bertoni S, Ravassard P, Manenti F, Piemonti L, Ferlenghi F, Lodola A, Tognolini M. Giorgio C, et al. Among authors: incerti m. Pharmacol Res. 2019 Mar;141:319-330. doi: 10.1016/j.phrs.2019.01.011. Epub 2019 Jan 6. Pharmacol Res. 2019. PMID: 30625359
109 results