Chen L - Search Results

1

Design and synthesis of novel mitochondria-targeted CDDO derivatives as potential anti-cancer agents.

Ju W, Li N, Wang J, Yu N, Lei Z, Zhang L, Sun J, Chen L. Ju W, et al. Among authors: chen l. Bioorg Chem. 2021 Oct;115:105249. doi: 10.1016/j.bioorg.2021.105249. Epub 2021 Aug 8. Bioorg Chem. 2021. PMID: 34390971

2

O²-(2,4-dinitrophenyl)diazeniumdiolates derivatives: Design, synthesis, cytotoxic evaluation and reversing MDR in MCF-7/ADR cells.

Li Q, Zou P, Sun J, Chen L. Li Q, et al. Among authors: chen l. Eur J Med Chem. 2018 Jan 1;143:732-744. doi: 10.1016/j.ejmech.2017.11.081. Eur J Med Chem. 2018. PMID: 29220794

3

Novel anticancer hybrids from diazen-1-ium-1,2-diolate nitric oxide donor and ROS inducer plumbagin: Design, synthesis and biological evaluations.

Bao N, Ou J, Li N, Zou P, Sun J, Chen L. Bao N, et al. Among authors: chen l. Eur J Med Chem. 2018 Jun 25;154:1-8. doi: 10.1016/j.ejmech.2018.04.047. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29772386

4

Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities.

Li N, Xu M, Bao N, Shi W, Li Q, Zhang X, Sun J, Chen L. Li N, et al. Among authors: chen l. Eur J Med Chem. 2018 Dec 5;160:1-8. doi: 10.1016/j.ejmech.2018.10.013. Epub 2018 Oct 6. Eur J Med Chem. 2018. PMID: 30316059

5

Artemisinin-indole and artemisinin-imidazole hybrids: Synthesis, cytotoxic evaluation and reversal effects on multidrug resistance in MCF-7/ADR cells.

Hu Y, Li N, Zhang J, Wang Y, Chen L, Sun J. Hu Y, et al. Among authors: chen l. Bioorg Med Chem Lett. 2019 May 1;29(9):1138-1142. doi: 10.1016/j.bmcl.2019.02.021. Epub 2019 Feb 20. Bioorg Med Chem Lett. 2019. PMID: 30837097

6

Design, synthesis and antitumor evaluation of novel celastrol derivatives.

Xu M, Li N, Zhao Z, Shi Z, Sun J, Chen L. Xu M, et al. Among authors: chen l. Eur J Med Chem. 2019 Jul 15;174:265-276. doi: 10.1016/j.ejmech.2019.04.050. Epub 2019 Apr 21. Eur J Med Chem. 2019. PMID: 31051401

7

Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest.

Shi Z, Li N, Chen C, Wang Y, Lei Z, Chen L, Sun J. Shi Z, et al. Among authors: chen l, chen c. Eur J Med Chem. 2020 Aug 15;200:112386. doi: 10.1016/j.ejmech.2020.112386. Epub 2020 May 6. Eur J Med Chem. 2020. PMID: 32438251

8

Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition.

Li N, Ou J, Bao N, Chen C, Shi Z, Chen L, Sun J. Li N, et al. Among authors: chen l, chen c. Bioorg Chem. 2020 Nov;104:104208. doi: 10.1016/j.bioorg.2020.104208. Epub 2020 Aug 28. Bioorg Chem. 2020. PMID: 32919131

9

Development of Furo[2,3-b]quinoline Derivatives with Anti-Breast Cancer Property by Targeting Topoisomerase II.

Wang Y, Li N, Jiang N, Chen L, Sun J. Wang Y, et al. Among authors: chen l. Anticancer Agents Med Chem. 2021;21(12):1482-1489. doi: 10.2174/1871520620999201103201348. Anticancer Agents Med Chem. 2021. PMID: 33155915

10

Novel Scopoletin Derivatives Kill Cancer Cells by Inducing Mitochondrial Depolarization and Apoptosis.

Shi Z, Chen L, Sun J. Shi Z, et al. Among authors: chen l. Anticancer Agents Med Chem. 2021;21(14):1774-1782. doi: 10.2174/1871520621666201207094416. Anticancer Agents Med Chem. 2021. PMID: 33292145

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