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mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors.
Lewis CS, Elnakat Thomas H, Orr-Asman MA, Green LC, Boody RE, Matiash K, Karve A, Hisada YM, Davis HW, Qi X, Mercer CA, Lucas FV, Aronow BJ, Mackman N, Versteeg HH, Bogdanov VY. Lewis CS, et al. Among authors: karve a. J Thromb Haemost. 2019 Jan;17(1):169-182. doi: 10.1111/jth.14342. Epub 2018 Dec 25. J Thromb Haemost. 2019. PMID: 30472780 Free PMC article.
Reuse of Molecules for Glioblastoma Therapy.
Koehler A, Karve A, Desai P, Arbiser J, Plas DR, Qi X, Read RD, Sasaki AT, Gawali VS, Toukam DK, Bhattacharya D, Kallay L, Pomeranz Krummel DA, Sengupta S. Koehler A, et al. Among authors: karve a. Pharmaceuticals (Basel). 2021 Jan 28;14(2):99. doi: 10.3390/ph14020099. Pharmaceuticals (Basel). 2021. PMID: 33525329 Free PMC article. Review.
Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth.
Mishra R, Yuan L, Patel H, Karve AS, Zhu H, White A, Alanazi S, Desai P, Merino EJ, Garrett JT. Mishra R, et al. Among authors: karve as. Int J Mol Sci. 2021 Feb 19;22(4):2088. doi: 10.3390/ijms22042088. Int J Mol Sci. 2021. PMID: 33669867 Free PMC article.
A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas.
Desai PB, Karve AS, Zawit M, Arora P, Dave N, Awosika J, Li N, Fuhrman B, Medvedovic M, Sallans L, Kendler A, DasGupta B, Plas D, Curry R, Zuccarello M, Chaudhary R, Sengupta S, Wise-Draper TM. Desai PB, et al. Among authors: karve as. Clin Cancer Res. 2024 May 15;30(10):2068-2077. doi: 10.1158/1078-0432.CCR-23-3341. Clin Cancer Res. 2024. PMID: 38530160 Clinical Trial.
GABA(A) Receptor Activation Drives GABARAP-Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors.
Bhattacharya D, Barrile R, Toukam DK, Gawali VS, Kallay L, Ahmed T, Brown H, Rezvanian S, Karve A, Desai PB, Medvedovic M, Wang K, Ionascu D, Harun N, Vallabhapurapu S, Wang C, Qi X, Baschnagel AM, Kritzer JA, Cook JM, Pomeranz Krummel DA, Sengupta S. Bhattacharya D, et al. Among authors: karve a. Cancers (Basel). 2024 Sep 15;16(18):3167. doi: 10.3390/cancers16183167. Cancers (Basel). 2024. PMID: 39335139 Free PMC article.
Pharmacokinetics of Levetiracetam Seizure Prophylaxis in Severe Traumatic Brain Injury.
Harlan SS, Philpott CD, Keegan SP, Droege ME, Karve AS, Foreman B, Wakefield D, Mueller EW, Sangha K, Ngwenya LB, Courter JD, Desai P, Droege C. Harlan SS, et al. Among authors: karve as. Ann Pharmacother. 2024 Jul;58(7):705-714. doi: 10.1177/10600280231202246. Epub 2023 Sep 30. Ann Pharmacother. 2024. PMID: 37776163
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