Opitz T - Search Results

1

Ste20-like Kinase Is Critical for Inhibitory Synapse Maintenance and Its Deficiency Confers a Developmental Dendritopathy.

Schoch S, Quatraccioni A, Robens BK, Maresch R, van Loo KMJ, Cases-Cunillera S, Kelly T, Opitz T, Borger V, Dietrich D, Pitsch J, Beck H, Becker AJ. Schoch S, et al. Among authors: opitz t. J Neurosci. 2021 Sep 29;41(39):8111-8125. doi: 10.1523/JNEUROSCI.0352-21.2021. Epub 2021 Aug 16. J Neurosci. 2021. PMID: 34400520 Free PMC article.

2

Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy.

Becker AJ, Pitsch J, Sochivko D, Opitz T, Staniek M, Chen CC, Campbell KP, Schoch S, Yaari Y, Beck H. Becker AJ, et al. Among authors: opitz t. J Neurosci. 2008 Dec 3;28(49):13341-53. doi: 10.1523/JNEUROSCI.1421-08.2008. J Neurosci. 2008. PMID: 19052226 Free PMC article.

3

Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currents.

Uebachs M, Opitz T, Royeck M, Dickhof G, Horstmann MT, Isom LL, Beck H. Uebachs M, et al. Among authors: opitz t. J Neurosci. 2010 Jun 23;30(25):8489-501. doi: 10.1523/JNEUROSCI.1534-10.2010. J Neurosci. 2010. PMID: 20573896 Free PMC article.

4

Stable mossy fiber long-term potentiation requires calcium influx at the granule cell soma, protein synthesis, and microtubule-dependent axonal transport.

Barnes SJ, Opitz T, Merkens M, Kelly T, von der Brelie C, Krueppel R, Beck H. Barnes SJ, et al. Among authors: opitz t. J Neurosci. 2010 Sep 29;30(39):12996-3004. doi: 10.1523/JNEUROSCI.1847-10.2010. J Neurosci. 2010. PMID: 20881117 Free PMC article.

5

The presynaptic active zone protein RIM1α controls epileptogenesis following status epilepticus.

Pitsch J, Opitz T, Borm V, Woitecki A, Staniek M, Beck H, Becker AJ, Schoch S. Pitsch J, et al. Among authors: opitz t. J Neurosci. 2012 Sep 5;32(36):12384-95. doi: 10.1523/JNEUROSCI.0223-12.2012. J Neurosci. 2012. PMID: 22956829 Free PMC article.

6

Loss of β1 accessory Na+ channel subunits causes failure of carbamazepine, but not of lacosamide, in blocking high-frequency firing via differential effects on persistent Na+ currents.

Uebachs M, Albus C, Opitz T, Isom L, Niespodziany I, Wolff C, Beck H. Uebachs M, et al. Among authors: opitz t. Epilepsia. 2012 Nov;53(11):1959-67. doi: 10.1111/j.1528-1167.2012.03675.x. Epub 2012 Sep 27. Epilepsia. 2012. PMID: 23016711 Free article.

7

RIM3γ and RIM4γ are key regulators of neuronal arborization.

Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S. Alvarez-Baron E, et al. Among authors: opitz t. J Neurosci. 2013 Jan 9;33(2):824-39. doi: 10.1523/JNEUROSCI.2229-12.2013. J Neurosci. 2013. PMID: 23303958 Free PMC article.

8

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1.

van Loo KM, Schaub C, Pitsch J, Kulbida R, Opitz T, Ekstein D, Dalal A, Urbach H, Beck H, Yaari Y, Schoch S, Becker AJ. van Loo KM, et al. Among authors: opitz t. Nat Commun. 2015 Oct 26;6:8688. doi: 10.1038/ncomms9688. Nat Commun. 2015. PMID: 26498180 Free PMC article.

9

Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus.

Royeck M, Kelly T, Opitz T, Otte DM, Rennhack A, Woitecki A, Pitsch J, Becker A, Schoch S, Kaupp UB, Yaari Y, Zimmer A, Beck H. Royeck M, et al. Among authors: opitz t. J Neurosci. 2015 Nov 18;35(46):15240-53. doi: 10.1523/JNEUROSCI.0493-15.2015. J Neurosci. 2015. PMID: 26586813 Free PMC article.

10

Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na⁺ channel inactivation.

Holtkamp D, Opitz T, Niespodziany I, Wolff C, Beck H. Holtkamp D, et al. Among authors: opitz t. Epilepsia. 2017 Jan;58(1):27-41. doi: 10.1111/epi.13602. Epub 2016 Nov 19. Epilepsia. 2017. PMID: 27864845 Free article.

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