Nitsche C - Search Results

1

Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors.

Ullrich S, Sasi VM, Mahawaththa MC, Ekanayake KB, Morewood R, George J, Shuttleworth L, Zhang X, Whitefield C, Otting G, Jackson C, Nitsche C. Ullrich S, et al. Among authors: nitsche c. Bioorg Med Chem Lett. 2021 Oct 15;50:128333. doi: 10.1016/j.bmcl.2021.128333. Epub 2021 Aug 19. Bioorg Med Chem Lett. 2021. PMID: 34418570 Free PMC article.

2

Thiazolidinone-peptide hybrids as dengue virus protease inhibitors with antiviral activity in cell culture.

Nitsche C, Schreier VN, Behnam MA, Kumar A, Bartenschlager R, Klein CD. Nitsche C, et al. J Med Chem. 2013 Nov 14;56(21):8389-403. doi: 10.1021/jm400828u. Epub 2013 Oct 22. J Med Chem. 2013. PMID: 24083834

3

The dengue virus NS2B-NS3 protease retains the closed conformation in the complex with BPTI.

Chen WN, Loscha KV, Nitsche C, Graham B, Otting G. Chen WN, et al. Among authors: nitsche c. FEBS Lett. 2014 Jun 27;588(14):2206-11. doi: 10.1016/j.febslet.2014.05.018. Epub 2014 May 21. FEBS Lett. 2014. PMID: 24859037 Free article.

4

Phenylalanine and Phenylglycine Analogues as Arginine Mimetics in Dengue Protease Inhibitors.

Weigel LF, Nitsche C, Graf D, Bartenschlager R, Klein CD. Weigel LF, et al. Among authors: nitsche c. J Med Chem. 2015 Oct 8;58(19):7719-33. doi: 10.1021/acs.jmedchem.5b00612. Epub 2015 Sep 30. J Med Chem. 2015. PMID: 26367391

5

Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets.

Chen WN, Nitsche C, Pilla KB, Graham B, Huber T, Klein CD, Otting G. Chen WN, et al. Among authors: nitsche c. J Am Chem Soc. 2016 Apr 6;138(13):4539-46. doi: 10.1021/jacs.6b00416. Epub 2016 Mar 24. J Am Chem Soc. 2016. PMID: 26974502 Free article.

6

Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags.

Nitsche C, Otting G. Nitsche C, et al. Prog Nucl Magn Reson Spectrosc. 2017 Feb;98-99:20-49. doi: 10.1016/j.pnmrs.2016.11.001. Epub 2016 Dec 1. Prog Nucl Magn Reson Spectrosc. 2017. PMID: 28283085 Review. No abstract available.

7

Solution conformations of a linked construct of the Zika virus NS2B-NS3 protease.

Mahawaththa MC, Pearce BJG, Szabo M, Graham B, Klein CD, Nitsche C, Otting G. Mahawaththa MC, et al. Among authors: nitsche c. Antiviral Res. 2017 Jun;142:141-147. doi: 10.1016/j.antiviral.2017.03.011. Epub 2017 Mar 21. Antiviral Res. 2017. PMID: 28336347

8

Site-selective tagging of proteins by pnictogen-mediated self-assembly.

Nitsche C, Mahawaththa MC, Becker W, Huber T, Otting G. Nitsche C, et al. Chem Commun (Camb). 2017 Oct 3;53(79):10894-10897. doi: 10.1039/c7cc06155b. Chem Commun (Camb). 2017. PMID: 28890978

9

NMR studies of ligand binding.

Nitsche C, Otting G. Nitsche C, et al. Curr Opin Struct Biol. 2018 Feb;48:16-22. doi: 10.1016/j.sbi.2017.09.001. Epub 2017 Oct 7. Curr Opin Struct Biol. 2018. PMID: 29017071 Review.

10

Trimethylsilyl tag for probing protein-ligand interactions by NMR.

Becker W, Adams LA, Graham B, Wagner GE, Zangger K, Otting G, Nitsche C. Becker W, et al. Among authors: nitsche c. J Biomol NMR. 2018 Apr;70(4):211-218. doi: 10.1007/s10858-018-0173-6. Epub 2018 Mar 21. J Biomol NMR. 2018. PMID: 29564580

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