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Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP.
Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL. Yu FX, et al. Cancer Cell. 2014 Jun 16;25(6):822-30. doi: 10.1016/j.ccr.2014.04.017. Epub 2014 May 29. Cancer Cell. 2014. PMID: 24882516 Free PMC article.
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.
Moroishi T, Park HW, Qin B, Chen Q, Meng Z, Plouffe SW, Taniguchi K, Yu FX, Karin M, Pan D, Guan KL. Moroishi T, et al. Among authors: yu fx. Genes Dev. 2015 Jun 15;29(12):1271-84. doi: 10.1101/gad.262816.115. Genes Dev. 2015. PMID: 26109050 Free PMC article.
Alternative Wnt Signaling Activates YAP/TAZ.
Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Park HW, et al. Among authors: yu b, yu fx. Cell. 2015 Aug 13;162(4):780-94. doi: 10.1016/j.cell.2015.07.013. Cell. 2015. PMID: 26276632 Free PMC article.
The Hippo pathway in tissue homeostasis and regeneration.
Wang Y, Yu A, Yu FX. Wang Y, et al. Among authors: yu a, yu fx. Protein Cell. 2017 May;8(5):349-359. doi: 10.1007/s13238-017-0371-0. Epub 2017 Jan 27. Protein Cell. 2017. PMID: 28130761 Free PMC article. Review.
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, Yang C, Marconett CN, Laird-Offringa IA, Minoo P, Guan K, Stripp BR, Crandall ED, Borok Z. Zhou B, et al. Among authors: yu fx. J Clin Invest. 2018 Mar 1;128(3):970-984. doi: 10.1172/JCI90429. Epub 2018 Feb 5. J Clin Invest. 2018. PMID: 29400695 Free PMC article.
169 results