Chen W - Search Results

1

α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship.

Chen P, Wang S, Cao C, Ye W, Wang M, Zhou C, Chen W, Zhang X, Zhang K, Zhou W. Chen P, et al. Among authors: chen w. Bioorg Chem. 2021 Nov;116:105295. doi: 10.1016/j.bioorg.2021.105295. Epub 2021 Aug 21. Bioorg Chem. 2021. PMID: 34455300

2

Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation.

Zhou L, Chen W, Cao C, Shi Y, Ye W, Hu J, Wang L, Zhou W. Zhou L, et al. Among authors: chen w. Eur J Med Chem. 2020 Mar 1;189:112028. doi: 10.1016/j.ejmech.2019.112028. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31945665

3

Oligosaccharide-camptothecin conjugates as potential antineoplastic drugs: Design, synthesis and biological evaluation.

Li M, Ye W, Fu K, Zhou C, Shi Y, Huang W, Chen W, Hu J, Jiang Z, Zhou W. Li M, et al. Among authors: chen w. Eur J Med Chem. 2020 Sep 15;202:112509. doi: 10.1016/j.ejmech.2020.112509. Epub 2020 Jun 30. Eur J Med Chem. 2020. PMID: 32668379

4

A gulose moiety contributes to the belomycin (BLM) disaccharide selective targeting to lung cancer cells.

Zhou C, Ye W, Cao Y, Wang M, Qi D, Liao G, Li H, Huang W, Chen W, Wang X, Zhou W. Zhou C, et al. Among authors: chen w. Eur J Med Chem. 2021 Dec 15;226:113866. doi: 10.1016/j.ejmech.2021.113866. Epub 2021 Sep 23. Eur J Med Chem. 2021. PMID: 34619466

5

Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives.

Chen W, Zhou C, Chen J, Wang M, Zhou F, Wang C, Zhang X, Zhou W. Chen W, et al. Among authors: chen j. Bioorg Chem. 2022 Feb;119:105515. doi: 10.1016/j.bioorg.2021.105515. Epub 2021 Dec 5. Bioorg Chem. 2022. PMID: 34896919

6

Abnormal saccharides affecting cancer multi-drug resistance (MDR) and the reversal strategies.

Wang M, Chen W, Chen J, Yuan S, Hu J, Han B, Huang Y, Zhou W. Wang M, et al. Among authors: chen j, chen w. Eur J Med Chem. 2021 Aug 5;220:113487. doi: 10.1016/j.ejmech.2021.113487. Epub 2021 Apr 23. Eur J Med Chem. 2021. PMID: 33933752 Review.

7

Design and synthesis of orally bioavailable aminopyrrolidinone histone deacetylase 6 inhibitors.

Lin X, Chen W, Qiu Z, Guo L, Zhu W, Li W, Wang Z, Zhang W, Zhang Z, Rong Y, Zhang M, Yu L, Zhong S, Zhao R, Wu X, Wong JC, Tang G. Lin X, et al. Among authors: chen w. J Med Chem. 2015 Mar 26;58(6):2809-20. doi: 10.1021/jm502011f. Epub 2015 Mar 13. J Med Chem. 2015. PMID: 25734520

8

Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors.

Qiu Z, Lin X, Zhou M, Liu Y, Zhu W, Chen W, Zhang W, Guo L, Liu H, Wu G, Huang M, Jiang M, Xu Z, Zhou Z, Qin N, Ren S, Qiu H, Zhong S, Zhang Y, Zhang Y, Wu X, Shi L, Shen F, Mao Y, Zhou X, Yang W, Wu JZ, Yang G, Mayweg AV, Shen HC, Tang G. Qiu Z, et al. Among authors: chen w. J Med Chem. 2016 Aug 25;59(16):7651-66. doi: 10.1021/acs.jmedchem.6b00879. Epub 2016 Aug 10. J Med Chem. 2016. PMID: 27458651

9

Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays.

Campbell RM, Cartwright C, Chen W, Chen Y, Duzic E, Fu JM, Loveland M, Manning R, McKibben B, Pleiman CM, Silverman L, Trueheart J, Webb DR, Wilkinson V, Witter DJ, Xie X, Castelhano AL. Campbell RM, et al. Among authors: chen w, chen y. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2413-8. doi: 10.1016/s0960-894x(99)00398-4. Bioorg Med Chem Lett. 1999. PMID: 10476879

10

Identification of E2F-1/Cyclin A antagonists.

Sharma SK, Ramsey TM, Chen YN, Chen W, Martin MS, Clune K, Sabio M, Bair KW. Sharma SK, et al. Among authors: chen yn, chen w. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2449-52. doi: 10.1016/s0960-894x(01)00486-3. Bioorg Med Chem Lett. 2001. PMID: 11549444

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