Zhang X - Search Results

1

α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship.

Chen P, Wang S, Cao C, Ye W, Wang M, Zhou C, Chen W, Zhang X, Zhang K, Zhou W. Chen P, et al. Among authors: zhang k, zhang x. Bioorg Chem. 2021 Nov;116:105295. doi: 10.1016/j.bioorg.2021.105295. Epub 2021 Aug 21. Bioorg Chem. 2021. PMID: 34455300

2

Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.

Cui J, Meng Q, Zhang X, Cui Q, Zhou W, Li S. Cui J, et al. Among authors: zhang x. J Med Chem. 2015 Apr 23;58(8):3534-47. doi: 10.1021/acs.jmedchem.5b00265. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25799264

3

Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives.

Chen W, Zhou C, Chen J, Wang M, Zhou F, Wang C, Zhang X, Zhou W. Chen W, et al. Among authors: zhang x. Bioorg Chem. 2022 Feb;119:105515. doi: 10.1016/j.bioorg.2021.105515. Epub 2021 Dec 5. Bioorg Chem. 2022. PMID: 34896919

4

Regioselective semi-synthesis of 6-isomers of 5,8-O-dimethyl ether of shikonin derivatives via an 'intramolecular ring-closing/ring-opening' strategy as potent anticancer agents.

Zhou L, Zhang X, Zhou W. Zhou L, et al. Among authors: zhang x. Chem Cent J. 2017 Aug 2;11(1):74. doi: 10.1186/s13065-017-0306-0. Chem Cent J. 2017. PMID: 29086846 Free PMC article.

5

Advance in Anti-tumor Mechanisms of Shikonin, Alkannin and their Derivatives.

Zhang X, Cui JH, Meng QQ, Li SS, Zhou W, Xiao S. Zhang X, et al. Mini Rev Med Chem. 2018;18(2):164-172. doi: 10.2174/1389557517666170228114809. Mini Rev Med Chem. 2018. PMID: 28245783 Review.

6

Design, synthesis, and biological evaluation of shikonin and alkannin derivatives as potential anticancer agents via a prodrug approach.

Wang RB, Zhou W, Meng QQ, Zhang X, Ding J, Xu Y, Song HL, Yang K, Cui JH, Li SS. Wang RB, et al. Among authors: zhang x. ChemMedChem. 2014 Dec;9(12):2798-808. doi: 10.1002/cmdc.201402224. Epub 2014 Sep 18. ChemMedChem. 2014. PMID: 25234005

7

Quality components and antidepressant-like effects of GABA green tea.

Teng J, Zhou W, Zeng Z, Zhao W, Huang Y, Zhang X. Teng J, et al. Among authors: zhang x. Food Funct. 2017 Sep 20;8(9):3311-3318. doi: 10.1039/c7fo01045a. Food Funct. 2017. PMID: 28836632

8

Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer.

Li W, Li N, Tang Y, Li B, Liu L, Zhang X, Fu H, Duan JA. Li W, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6085-8. doi: 10.1016/j.bmcl.2012.08.038. Epub 2012 Aug 16. Bioorg Med Chem Lett. 2012. PMID: 22954735

9

Antitumor activity of DMAKO-05, a novel shikonin derivative, and its metabolism in rat liver microsome.

Zhang X, Wang RB, Zhou W, Xiao S, Meng QQ, Li SS. Zhang X, et al. AAPS PharmSciTech. 2015 Apr;16(2):259-66. doi: 10.1208/s12249-014-0217-5. Epub 2014 Oct 2. AAPS PharmSciTech. 2015. PMID: 25273027 Free PMC article.

10

Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor.

Zhang X, Peng T, Ji X, Li J, Tong L, Li Z, Yang W, Xu Y, Li M, Ding J, Jiang H, Xie H, Liu H. Zhang X, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7988-98. doi: 10.1016/j.bmc.2013.09.049. Epub 2013 Oct 2. Bioorg Med Chem. 2013. PMID: 24183742

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