Zhou W - Search Results

1

α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship.

Chen P, Wang S, Cao C, Ye W, Wang M, Zhou C, Chen W, Zhang X, Zhang K, Zhou W. Chen P, et al. Among authors: zhou w, zhou c. Bioorg Chem. 2021 Nov;116:105295. doi: 10.1016/j.bioorg.2021.105295. Epub 2021 Aug 21. Bioorg Chem. 2021. PMID: 34455300

2

Semi-synthesis and antitumor activity of 6-isomers of 5, 8-O-dimethyl acylshikonin derivatives.

Zhou W, Zhang X, Xiao L, Ding J, Liu QH, Li SS. Zhou W, et al. Eur J Med Chem. 2011 Aug;46(8):3420-7. doi: 10.1016/j.ejmech.2011.05.006. Epub 2011 May 12. Eur J Med Chem. 2011. PMID: 21620530

3

Design, synthesis, and biological evaluation of shikonin and alkannin derivatives as potential anticancer agents via a prodrug approach.

Wang RB, Zhou W, Meng QQ, Zhang X, Ding J, Xu Y, Song HL, Yang K, Cui JH, Li SS. Wang RB, et al. Among authors: zhou w. ChemMedChem. 2014 Dec;9(12):2798-808. doi: 10.1002/cmdc.201402224. Epub 2014 Sep 18. ChemMedChem. 2014. PMID: 25234005

4

Antitumor activity of DMAKO-05, a novel shikonin derivative, and its metabolism in rat liver microsome.

Zhang X, Wang RB, Zhou W, Xiao S, Meng QQ, Li SS. Zhang X, et al. Among authors: zhou w. AAPS PharmSciTech. 2015 Apr;16(2):259-66. doi: 10.1208/s12249-014-0217-5. Epub 2014 Oct 2. AAPS PharmSciTech. 2015. PMID: 25273027 Free PMC article.

5

Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.

Cui J, Meng Q, Zhang X, Cui Q, Zhou W, Li S. Cui J, et al. Among authors: zhou w. J Med Chem. 2015 Apr 23;58(8):3534-47. doi: 10.1021/acs.jmedchem.5b00265. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25799264

6

Advance in Anti-tumor Mechanisms of Shikonin, Alkannin and their Derivatives.

Zhang X, Cui JH, Meng QQ, Li SS, Zhou W, Xiao S. Zhang X, et al. Among authors: zhou w. Mini Rev Med Chem. 2018;18(2):164-172. doi: 10.2174/1389557517666170228114809. Mini Rev Med Chem. 2018. PMID: 28245783 Review.

7

Quality components and antidepressant-like effects of GABA green tea.

Teng J, Zhou W, Zeng Z, Zhao W, Huang Y, Zhang X. Teng J, et al. Among authors: zhou w. Food Funct. 2017 Sep 20;8(9):3311-3318. doi: 10.1039/c7fo01045a. Food Funct. 2017. PMID: 28836632

8

Regioselective semi-synthesis of 6-isomers of 5,8-O-dimethyl ether of shikonin derivatives via an 'intramolecular ring-closing/ring-opening' strategy as potent anticancer agents.

Zhou L, Zhang X, Zhou W. Zhou L, et al. Among authors: zhou w. Chem Cent J. 2017 Aug 2;11(1):74. doi: 10.1186/s13065-017-0306-0. Chem Cent J. 2017. PMID: 29086846 Free PMC article.

9

Design and synthesis of structurally defined heparan sulfate (HS)-FK506 conjugates as an exogenous approach to investigate biological functions of nucleus HS.

Li M, Yuan S, Chen J, Lv L, Guo S, Zhou W. Li M, et al. Among authors: zhou w. Bioorg Chem. 2018 Dec;81:203-210. doi: 10.1016/j.bioorg.2018.08.015. Epub 2018 Aug 16. Bioorg Chem. 2018. PMID: 30144633

10

Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation.

Zhou L, Chen W, Cao C, Shi Y, Ye W, Hu J, Wang L, Zhou W. Zhou L, et al. Among authors: zhou w. Eur J Med Chem. 2020 Mar 1;189:112028. doi: 10.1016/j.ejmech.2019.112028. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31945665

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