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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors.
Seixas JD, Sousa BB, Marques MC, Guerreiro A, Traquete R, Rodrigues T, Albuquerque IS, Sousa MFQ, Lemos AR, Sousa PMF, Bandeiras TM, Wu D, Doyle SK, Robinson CV, Koehler AN, Corzana F, Matias PM, Bernardes GJL. Seixas JD, et al. Among authors: corzana f. RSC Chem Biol. 2020 Aug 28;1(4):251-262. doi: 10.1039/d0cb00033g. eCollection 2020 Oct 1. RSC Chem Biol. 2020. PMID: 34458764 Free PMC article.
Turning universal O into rare Bombay type blood.
Anso I, Naegeli A, Cifuente JO, Orrantia A, Andersson E, Zenarruzabeitia O, Moraleda-Montoya A, García-Alija M, Corzana F, Del Orbe RA, Borrego F, Trastoy B, Sjögren J, Guerin ME. Anso I, et al. Among authors: corzana f. Nat Commun. 2023 Mar 30;14(1):1765. doi: 10.1038/s41467-023-37324-z. Nat Commun. 2023. PMID: 36997505 Free PMC article.
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.
Lira-Navarrete E, de Las Rivas M, Compañón I, Pallarés MC, Kong Y, Iglesias-Fernández J, Bernardes GJ, Peregrina JM, Rovira C, Bernadó P, Bruscolini P, Clausen H, Lostao A, Corzana F, Hurtado-Guerrero R. Lira-Navarrete E, et al. Among authors: corzana f. Nat Commun. 2015 May 5;6:6937. doi: 10.1038/ncomms7937. Nat Commun. 2015. PMID: 25939779 Free PMC article.
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
Martínez-Sáez N, Castro-López J, Valero-González J, Madariaga D, Compañón I, Somovilla VJ, Salvadó M, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Bernardes GJ, Peregrina JM, Hurtado-Guerrero R, Corzana F. Martínez-Sáez N, et al. Among authors: corzana f. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9830-4. doi: 10.1002/anie.201502813. Epub 2015 Jun 26. Angew Chem Int Ed Engl. 2015. PMID: 26118689 Free PMC article.
Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
Rodrigues T, Sieglitz F, Somovilla VJ, Cal PM, Galione A, Corzana F, Bernardes GJ. Rodrigues T, et al. Among authors: corzana f. Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11077-81. doi: 10.1002/anie.201604336. Epub 2016 Jul 8. Angew Chem Int Ed Engl. 2016. PMID: 27391219 Free PMC article.
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
Fernández EM, Navo CD, Martínez-Sáez N, Gonçalves-Pereira R, Somovilla VJ, Avenoza A, Busto JH, Bernardes GJ, Jiménez-Osés G, Corzana F, Fernández JM, Mellet CO, Peregrina JM. Fernández EM, et al. Among authors: corzana f. Org Lett. 2016 Aug 5;18(15):3890-3. doi: 10.1021/acs.orglett.6b01899. Epub 2016 Jul 25. Org Lett. 2016. PMID: 27453399
Site-Selective Modification of Proteins with Oxetanes.
Boutureira O, Martínez-Sáez N, Brindle KM, Neves AA, Corzana F, Bernardes GJL. Boutureira O, et al. Among authors: corzana f. Chemistry. 2017 May 11;23(27):6483-6489. doi: 10.1002/chem.201700745. Epub 2017 Mar 29. Chemistry. 2017. PMID: 28261889 Free PMC article.
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo.
Martínez-Sáez N, Sun S, Oldrini D, Sormanni P, Boutureira O, Carboni F, Compañón I, Deery MJ, Vendruscolo M, Corzana F, Adamo R, Bernardes GJL. Martínez-Sáez N, et al. Among authors: corzana f. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14963-14967. doi: 10.1002/anie.201708847. Epub 2017 Oct 20. Angew Chem Int Ed Engl. 2017. PMID: 28968001 Free PMC article.
151 results