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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors.
Seixas JD, Sousa BB, Marques MC, Guerreiro A, Traquete R, Rodrigues T, Albuquerque IS, Sousa MFQ, Lemos AR, Sousa PMF, Bandeiras TM, Wu D, Doyle SK, Robinson CV, Koehler AN, Corzana F, Matias PM, Bernardes GJL. Seixas JD, et al. Among authors: guerreiro a. RSC Chem Biol. 2020 Aug 28;1(4):251-262. doi: 10.1039/d0cb00033g. eCollection 2020 Oct 1. RSC Chem Biol. 2020. PMID: 34458764 Free PMC article.
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation.
Freedy AM, Matos MJ, Boutureira O, Corzana F, Guerreiro A, Akkapeddi P, Somovilla VJ, Rodrigues T, Nicholls K, Xie B, Jiménez-Osés G, Brindle KM, Neves AA, Bernardes GJL. Freedy AM, et al. Among authors: guerreiro a. J Am Chem Soc. 2017 Dec 20;139(50):18365-18375. doi: 10.1021/jacs.7b10702. Epub 2017 Dec 5. J Am Chem Soc. 2017. PMID: 29206031 Free PMC article.
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage.
Compañón I, Guerreiro A, Mangini V, Castro-López J, Escudero-Casao M, Avenoza A, Busto JH, Castillón S, Jiménez-Barbero J, Asensio JL, Jiménez-Osés G, Boutureira O, Peregrina JM, Hurtado-Guerrero R, Fiammengo R, Bernardes GJL, Corzana F. Compañón I, et al. Among authors: guerreiro a. J Am Chem Soc. 2019 Mar 6;141(9):4063-4072. doi: 10.1021/jacs.8b13503. Epub 2019 Feb 20. J Am Chem Soc. 2019. PMID: 30726084
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells.
Jiménez-Moreno E, Guo Z, Oliveira BL, Albuquerque IS, Kitowski A, Guerreiro A, Boutureira O, Rodrigues T, Jiménez-Osés G, Bernardes GJ. Jiménez-Moreno E, et al. Among authors: guerreiro a. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):243-247. doi: 10.1002/anie.201609607. Epub 2016 Dec 8. Angew Chem Int Ed Engl. 2017. PMID: 27930843 Free PMC article.
Chemo- and Regioselective Lysine Modification on Native Proteins.
Matos MJ, Oliveira BL, Martínez-Sáez N, Guerreiro A, Cal PMSD, Bertoldo J, Maneiro M, Perkins E, Howard J, Deery MJ, Chalker JM, Corzana F, Jiménez-Osés G, Bernardes GJL. Matos MJ, et al. Among authors: guerreiro a. J Am Chem Soc. 2018 Mar 21;140(11):4004-4017. doi: 10.1021/jacs.7b12874. Epub 2018 Mar 8. J Am Chem Soc. 2018. PMID: 29473744 Free PMC article.
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Conde J, Pumroy RA, Baker C, Rodrigues T, Guerreiro A, Sousa BB, Marques MC, de Almeida BP, Lee S, Leites EP, Picard D, Samanta A, Vaz SH, Sieglitz F, Langini M, Remke M, Roque R, Weiss T, Weller M, Liu Y, Han S, Corzana F, Morais VA, Faria CC, Carvalho T, Filippakopoulos P, Snijder B, Barbosa-Morais NL, Moiseenkova-Bell VY, Bernardes GJL. Conde J, et al. Among authors: guerreiro a. ACS Cent Sci. 2021 May 26;7(5):868-881. doi: 10.1021/acscentsci.1c00070. Epub 2021 Apr 14. ACS Cent Sci. 2021. PMID: 34079902 Free PMC article.
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment.
Bermejo IA, Navo CD, Castro-López J, Guerreiro A, Jiménez-Moreno E, Sánchez Fernández EM, García-Martín F, Hinou H, Nishimura SI, García Fernández JM, Mellet CO, Avenoza A, Busto JH, Bernardes GJL, Hurtado-Guerrero R, Peregrina JM, Corzana F. Bermejo IA, et al. Among authors: guerreiro a. Chem Sci. 2020 Mar 27;11(15):3996-4006. doi: 10.1039/c9sc06334j. Chem Sci. 2020. PMID: 34122869 Free PMC article.
Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation.
Ferhati X, Salas-Cubero M, Garrido P, García-Sanmartín J, Guerreiro A, Avenoza A, Busto JH, Peregrina JM, Martínez A, Jiménez-Moreno E, Bernardes GJL, Corzana F. Ferhati X, et al. Among authors: guerreiro a. Org Lett. 2021 Nov 5;23(21):8580-8584. doi: 10.1021/acs.orglett.1c03299. Epub 2021 Oct 25. Org Lett. 2021. PMID: 34694118 Free PMC article.
209 results