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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors.
Seixas JD, Sousa BB, Marques MC, Guerreiro A, Traquete R, Rodrigues T, Albuquerque IS, Sousa MFQ, Lemos AR, Sousa PMF, Bandeiras TM, Wu D, Doyle SK, Robinson CV, Koehler AN, Corzana F, Matias PM, Bernardes GJL. Seixas JD, et al. Among authors: sousa bb. RSC Chem Biol. 2020 Aug 28;1(4):251-262. doi: 10.1039/d0cb00033g. eCollection 2020 Oct 1. RSC Chem Biol. 2020. PMID: 34458764 Free PMC article.
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Conde J, Pumroy RA, Baker C, Rodrigues T, Guerreiro A, Sousa BB, Marques MC, de Almeida BP, Lee S, Leites EP, Picard D, Samanta A, Vaz SH, Sieglitz F, Langini M, Remke M, Roque R, Weiss T, Weller M, Liu Y, Han S, Corzana F, Morais VA, Faria CC, Carvalho T, Filippakopoulos P, Snijder B, Barbosa-Morais NL, Moiseenkova-Bell VY, Bernardes GJL. Conde J, et al. Among authors: sousa bb. ACS Cent Sci. 2021 May 26;7(5):868-881. doi: 10.1021/acscentsci.1c00070. Epub 2021 Apr 14. ACS Cent Sci. 2021. PMID: 34079902 Free PMC article.
Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo.
Kohs TCL, Olson SR, Pang J, Jordan KR, Zheng TJ, Xie A, Hodovan J, Muller M, McArthur C, Johnson J, Sousa BB, Wallisch M, Kievit P, Aslan JE, Seixas JD, Bernardes GJL, Hinds MT, Lindner JR, McCarty OJT, Puy C, Shatzel JJ. Kohs TCL, et al. Among authors: sousa bb. Cell Mol Bioeng. 2022 Apr 18;15(3):231-243. doi: 10.1007/s12195-022-00723-1. eCollection 2022 Jun. Cell Mol Bioeng. 2022. PMID: 35611166 Free PMC article.
Structural insights into TRPV2 activation by small molecules.
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY. Pumroy RA, et al. Among authors: sousa bb. Nat Commun. 2022 Apr 28;13(1):2334. doi: 10.1038/s41467-022-30083-3. Nat Commun. 2022. PMID: 35484159 Free PMC article.
P-cadherin role in normal breast development and cancer.
Albergaria A, Ribeiro AS, Vieira AF, Sousa B, Nobre AR, Seruca R, Schmitt F, Paredes J. Albergaria A, et al. Int J Dev Biol. 2011;55(7-9):811-22. doi: 10.1387/ijdb.113382aa. Int J Dev Biol. 2011. PMID: 22161837 Free article. Review.
50 results