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A non-clinical comparative study of IL-23 antibodies in psoriasis.
Zhou L, Wang Y, Wan Q, Wu F, Barbon J, Dunstan R, Gauld S, Konrad M, Leys L, McCarthy R, Namovic M, Nelson C, Overmeyer G, Perron D, Su Z, Wang L, Westmoreland S, Zhang J, Zhu R, Veldman G. Zhou L, et al. Among authors: veldman g. MAbs. 2021 Jan-Dec;13(1):1964420. doi: 10.1080/19420862.2021.1964420. MAbs. 2021. PMID: 34460338 Free PMC article.
Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models.
Huang L, Fung E, Bose S, Popp A, Böser P, Memmott J, Kutskova YA, Miller R, Tarcsa E, Klein C, Veldman GM, Mueller BK, Cui YF. Huang L, et al. Among authors: veldman gm. Neurobiol Dis. 2021 Nov;159:105492. doi: 10.1016/j.nbd.2021.105492. Epub 2021 Aug 31. Neurobiol Dis. 2021. PMID: 34478849 Free article.
A highly potent antibody effective against SARS-CoV-2 variants of concern.
Fenwick C, Turelli P, Perez L, Pellaton C, Esteves-Leuenberger L, Farina A, Campos J, Lana E, Fiscalini F, Raclot C, Pojer F, Lau K, Demurtas D, Descatoire M, Joo VS, Foglierini M, Noto A, Abdelnabi R, Foo CS, Vangeel L, Neyts J, Du W, Bosch BJ, Veldman G, Leyssen P, Thiel V, LeGrand R, Lévy Y, Trono D, Pantaleo G. Fenwick C, et al. Among authors: veldman g. Cell Rep. 2021 Oct 12;37(2):109814. doi: 10.1016/j.celrep.2021.109814. Epub 2021 Sep 21. Cell Rep. 2021. PMID: 34599871 Free PMC article.
A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins.
Kierzek AM, Hickling TP, Figueroa I, Kalvass JC, Nijsen M, Mohan K, Veldman GM, Yamada A, Sayama H, Yokoo S, Gulati A, Dhanikula RS, Gokemeijer J, Leil TA, Thalhauser CJ, Giorgi M, Swat MJ, Chelliah V, Small BG, Benson N, Walker M, Gadkar K, Quarmby V, Deng R, Ferrante A, Dickinson GL, Van Der Walt JS, Zhou L, Chen X, Jones HM, Narula J, Tourdot S, Lavé T, Ribba B, van der Graaf PH. Kierzek AM, et al. Among authors: veldman gm. CPT Pharmacometrics Syst Pharmacol. 2019 Nov;8(11):773-776. doi: 10.1002/psp4.12465. Epub 2019 Oct 8. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31529677 Free PMC article. No abstract available.
Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis.
Demicheva E, Cui YF, Bardwell P, Barghorn S, Kron M, Meyer AH, Schmidt M, Gerlach B, Leddy M, Barlow E, O'Connor E, Choi CH, Huang L, Veldman GM, Rus H, Shabanzadeh AP, Tassew NG, Monnier PP, Müller T, Calabresi PA, Schoemaker H, Mueller BK. Demicheva E, et al. Among authors: veldman gm. Cell Rep. 2015 Mar 24;10(11):1887-98. doi: 10.1016/j.celrep.2015.02.048. Cell Rep. 2015. PMID: 25801027 Free article.
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength.
Whittemore LA, Song K, Li X, Aghajanian J, Davies M, Girgenrath S, Hill JJ, Jalenak M, Kelley P, Knight A, Maylor R, O'Hara D, Pearson A, Quazi A, Ryerson S, Tan XY, Tomkinson KN, Veldman GM, Widom A, Wright JF, Wudyka S, Zhao L, Wolfman NM. Whittemore LA, et al. Biochem Biophys Res Commun. 2003 Jan 24;300(4):965-71. doi: 10.1016/s0006-291x(02)02953-4. Biochem Biophys Res Commun. 2003. PMID: 12559968
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.
Li J, Tomkinson KN, Tan XY, Wu P, Yan G, Spaulding V, Deng B, Annis-Freeman B, Heveron K, Zollner R, De Zutter G, Wright JF, Crawford TK, Liu W, Jacobs KA, Wolfman NM, Ling V, Pittman DD, Veldman GM, Fouser LA. Li J, et al. Among authors: veldman gm. Int Immunopharmacol. 2004 May;4(5):693-708. doi: 10.1016/j.intimp.2004.01.010. Int Immunopharmacol. 2004. PMID: 15120653 Review.
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses.
Bennett F, Luxenberg D, Ling V, Wang IM, Marquette K, Lowe D, Khan N, Veldman G, Jacobs KA, Valge-Archer VE, Collins M, Carreno BM. Bennett F, et al. Among authors: veldman g. J Immunol. 2003 Jan 15;170(2):711-8. doi: 10.4049/jimmunol.170.2.711. J Immunol. 2003. PMID: 12517932
31 results