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IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB- and caspase-8-dependent mechanisms.
Zhou L, Zhang Y, Meads MB, Dai Y, Ning Y, Hu X, Li L, Sharma K, Nkwocha J, Parker R, Bui D, McCarter J, Kramer L, Purcell C, Sudalagunta PR, Canevarolo RR, Coelho Siqueira Silva MD, De Avila G, Alugubelli RR, Silva AS, Kmeiciak M, Ferreira-Gonzalez A, Shain KH, Grant S. Zhou L, et al. Among authors: ferreira gonzalez a. Blood Adv. 2021 Oct 12;5(19):3776-3788. doi: 10.1182/bloodadvances.2020003597. Blood Adv. 2021. PMID: 34464977 Free PMC article.
Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation.
Rahmani M, Aust MM, Hawkins E, Parker RE, Ross M, Kmieciak M, Reshko LB, Rizzo KA, Dumur CI, Ferreira-Gonzalez A, Grant S. Rahmani M, et al. Haematologica. 2015 Dec;100(12):1553-63. doi: 10.3324/haematol.2015.130351. Epub 2015 Oct 9. Haematologica. 2015. PMID: 26452980 Free PMC article.
Favorable outcomes in patients with high donor-derived T cell count after in vivo T cell-depleted reduced-intensity allogeneic stem cell transplantation.
Toor AA, Sabo RT, Chung HM, Roberts C, Manjili RH, Song S, Williams DC Jr, Edmiston W, Gatesman ML, Edwards RW, Ferreira-Gonzalez A, Clark WB, Neale MC, McCarty JM, Manjili MH. Toor AA, et al. Biol Blood Marrow Transplant. 2012 May;18(5):794-804. doi: 10.1016/j.bbmt.2011.10.011. Epub 2011 Oct 17. Biol Blood Marrow Transplant. 2012. PMID: 22005648 Free PMC article. Clinical Trial.
Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential in HLA-Matched and -Mismatched Donor-Recipient Pairs.
Abdul Razzaq B, Scalora A, Koparde VN, Meier J, Mahmood M, Salman S, Jameson-Lee M, Serrano MG, Sheth N, Voelkner M, Kobulnicky DJ, Roberts CH, Ferreira-Gonzalez A, Manjili MH, Buck GA, Neale MC, Toor AA. Abdul Razzaq B, et al. Biol Blood Marrow Transplant. 2016 May;22(5):850-61. doi: 10.1016/j.bbmt.2015.11.1103. Epub 2015 Dec 11. Biol Blood Marrow Transplant. 2016. PMID: 26688192 Free PMC article.
86 results