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A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer.
Ali AI, Wang M, von Scheidt B, Dominguez PM, Harrison AJ, Tantalo DGM, Kang J, Oliver AJ, Chan JD, Du X, Bai Y, Lee B, Johnstone RW, Darcy PK, Kershaw MH, Slaney CY. Ali AI, et al. Among authors: du x. Clin Cancer Res. 2021 Nov 15;27(22):6222-6234. doi: 10.1158/1078-0432.CCR-21-1141. Epub 2021 Sep 2. Clin Cancer Res. 2021. PMID: 34475103
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
Wiede F, Lu KH, Du X, Liang S, Hochheiser K, Dodd GT, Goh PK, Kearney C, Meyran D, Beavis PA, Henderson MA, Park SL, Waithman J, Zhang S, Zhang ZY, Oliaro J, Gebhardt T, Darcy PK, Tiganis T. Wiede F, et al. Among authors: du x. EMBO J. 2020 Jan 15;39(2):e103637. doi: 10.15252/embj.2019103637. Epub 2019 Dec 5. EMBO J. 2020. PMID: 31803974 Free PMC article.
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