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A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing.
Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK. Biswas K, et al. Among authors: sharan sk. Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8. Cell Death Dis. 2021. PMID: 34489406 Free PMC article.
BRCA2 deficiency in mice leads to meiotic impairment and infertility.
Sharan SK, Pyle A, Coppola V, Babus J, Swaminathan S, Benedict J, Swing D, Martin BK, Tessarollo L, Evans JP, Flaws JA, Handel MA. Sharan SK, et al. Development. 2004 Jan;131(1):131-42. doi: 10.1242/dev.00888. Epub 2003 Dec 3. Development. 2004. PMID: 14660434
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.
Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK. Kuznetsov S, et al. Among authors: sharan sk. J Cell Biol. 2007 Feb 26;176(5):581-92. doi: 10.1083/jcb.200608130. Epub 2007 Feb 20. J Cell Biol. 2007. PMID: 17312021 Free PMC article.
101 results