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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
Bowen NE, Temple J, Shepard C, Oo A, Arizaga F, Kapoor-Vazirani P, Persaud M, Yu CH, Kim DH, Schinazi RF, Ivanov DN, Diaz-Griffero F, Yu DS, Xiong Y, Kim B. Bowen NE, et al. Among authors: kim b, kim dh. J Biol Chem. 2021 Oct;297(4):101170. doi: 10.1016/j.jbc.2021.101170. Epub 2021 Sep 4. J Biol Chem. 2021. PMID: 34492268 Free PMC article.
Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.
Hollenbaugh JA, Gee P, Baker J, Daly MB, Amie SM, Tate J, Kasai N, Kanemura Y, Kim DH, Ward BM, Koyanagi Y, Kim B. Hollenbaugh JA, et al. Among authors: kim b, kim dh. PLoS Pathog. 2013;9(6):e1003481. doi: 10.1371/journal.ppat.1003481. Epub 2013 Jun 27. PLoS Pathog. 2013. PMID: 23825958 Free PMC article. Clinical Trial.
Host SAMHD1 protein promotes HIV-1 recombination in macrophages.
Nguyen LA, Kim DH, Daly MB, Allan KC, Kim B. Nguyen LA, et al. Among authors: kim b, kim dh. J Biol Chem. 2014 Jan 31;289(5):2489-96. doi: 10.1074/jbc.C113.522326. Epub 2013 Dec 18. J Biol Chem. 2014. PMID: 24352659 Free PMC article.
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