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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
Bowen NE, Temple J, Shepard C, Oo A, Arizaga F, Kapoor-Vazirani P, Persaud M, Yu CH, Kim DH, Schinazi RF, Ivanov DN, Diaz-Griffero F, Yu DS, Xiong Y, Kim B. Bowen NE, et al. Among authors: oo a. J Biol Chem. 2021 Oct;297(4):101170. doi: 10.1016/j.jbc.2021.101170. Epub 2021 Sep 4. J Biol Chem. 2021. PMID: 34492268 Free PMC article.
Tetraspanin CD81 regulates HSV-1 infection.
Benayas B, Sastre I, López-Martín S, Oo A, Kim B, Bullido MJ, Aldudo J, Yáñez-Mó M. Benayas B, et al. Among authors: oo a. Med Microbiol Immunol. 2020 Aug;209(4):489-498. doi: 10.1007/s00430-020-00684-0. Epub 2020 Jun 4. Med Microbiol Immunol. 2020. PMID: 32500359 Free PMC article.
Repurposing Nucleoside Analogs for Human Coronaviruses.
Zandi K, Amblard F, Musall K, Downs-Bowen J, Kleinbard R, Oo A, Cao D, Liang B, Russell OO, McBrayer T, Bassit L, Kim B, Schinazi RF. Zandi K, et al. Among authors: oo a. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01652-20. doi: 10.1128/AAC.01652-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33122172 Free PMC article.
Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase.
Zandi K, Musall K, Oo A, Cao D, Liang B, Hassandarvish P, Lan S, Slack RL, Kirby KA, Bassit L, Amblard F, Kim B, AbuBakar S, Sarafianos SG, Schinazi RF. Zandi K, et al. Among authors: oo a. Microorganisms. 2021 Apr 22;9(5):893. doi: 10.3390/microorganisms9050893. Microorganisms. 2021. PMID: 33921971 Free PMC article.
Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels.
Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: oo a. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554731. doi: 10.1101/2023.08.24.554731. bioRxiv. 2023. Update in: mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23 PMID: 37662193 Free PMC article. Updated. Preprint.
269 results