Schinazi RF - Search Results

1

Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.

Bowen NE, Temple J, Shepard C, Oo A, Arizaga F, Kapoor-Vazirani P, Persaud M, Yu CH, Kim DH, Schinazi RF, Ivanov DN, Diaz-Griffero F, Yu DS, Xiong Y, Kim B. Bowen NE, et al. Among authors: schinazi rf. J Biol Chem. 2021 Oct;297(4):101170. doi: 10.1016/j.jbc.2021.101170. Epub 2021 Sep 4. J Biol Chem. 2021. PMID: 34492268 Free PMC article.

2

Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase.

Domaoal RA, McMahon M, Thio CL, Bailey CM, Tirado-Rives J, Obikhod A, Detorio M, Rapp KL, Siliciano RF, Schinazi RF, Anderson KS. Domaoal RA, et al. Among authors: schinazi rf. J Biol Chem. 2008 Feb 29;283(9):5452-9. doi: 10.1074/jbc.M707834200. Epub 2007 Oct 25. J Biol Chem. 2008. PMID: 17962184 Free PMC article.

3

Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages.

Kennedy EM, Gavegnano C, Nguyen L, Slater R, Lucas A, Fromentin E, Schinazi RF, Kim B. Kennedy EM, et al. Among authors: schinazi rf. J Biol Chem. 2010 Dec 10;285(50):39380-91. doi: 10.1074/jbc.M110.178582. Epub 2010 Oct 5. J Biol Chem. 2010. PMID: 20924117 Free PMC article.

4

Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.

Kennedy EM, Daddacha W, Slater R, Gavegnano C, Fromentin E, Schinazi RF, Kim B. Kennedy EM, et al. Among authors: schinazi rf. J Biol Chem. 2011 Jul 15;286(28):25047-55. doi: 10.1074/jbc.M111.234047. Epub 2011 Mar 31. J Biol Chem. 2011. PMID: 21454906 Free PMC article.

5

The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents.

Gavegnano C, Kennedy EM, Kim B, Schinazi RF. Gavegnano C, et al. Among authors: schinazi rf. Mol Biol Int. 2012;2012:625983. doi: 10.1155/2012/625983. Epub 2012 Jul 1. Mol Biol Int. 2012. PMID: 22811909 Free PMC article.

6

Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels.

Amie SM, Daly MB, Noble E, Schinazi RF, Bambara RA, Kim B. Amie SM, et al. Among authors: schinazi rf. J Biol Chem. 2013 Jul 12;288(28):20683-91. doi: 10.1074/jbc.M113.472159. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23744077 Free PMC article.

7

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

Hollenbaugh JA, Tao S, Lenzi GM, Ryu S, Kim DH, Diaz-Griffero F, Schinazi RF, Kim B. Hollenbaugh JA, et al. Among authors: schinazi rf. Retrovirology. 2014 Aug 27;11:63. doi: 10.1186/s12977-014-0063-2. Retrovirology. 2014. PMID: 25158827 Free PMC article.

8

Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses.

Lenzi GM, Domaoal RA, Kim DH, Schinazi RF, Kim B. Lenzi GM, et al. Among authors: schinazi rf. Retrovirology. 2014 Dec 19;11:111. doi: 10.1186/s12977-014-0111-y. Retrovirology. 2014. PMID: 25524560 Free PMC article.

9

Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.

Nguyen LA, Domaoal RA, Kennedy EM, Kim DH, Schinazi RF, Kim B. Nguyen LA, et al. Among authors: schinazi rf. Antiviral Res. 2015 Mar;115:75-82. doi: 10.1016/j.antiviral.2014.12.016. Epub 2014 Dec 31. Antiviral Res. 2015. PMID: 25557601 Free PMC article.

10

Differential regulatory activities of viral protein X for anti-viral efficacy of nucleos(t)ide reverse transcriptase inhibitors in monocyte-derived macrophages and activated CD4(+) T cells.

Hollenbaugh JA, Schader SM, Schinazi RF, Kim B. Hollenbaugh JA, et al. Among authors: schinazi rf. Virology. 2015 Nov;485:313-21. doi: 10.1016/j.virol.2015.08.006. Epub 2015 Aug 29. Virology. 2015. PMID: 26319213 Free PMC article.

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