Alonso LG - Search Results

1

Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif.

Lorenzo R, Defelipe LA, Aliperti L, Niebling S, Custódio TF, Löw C, Schwarz JJ, Remans K, Craig PO, Otero LH, Klinke S, García-Alai M, Sánchez IE, Alonso LG. Lorenzo R, et al. Among authors: alonso lg. J Biol Chem. 2021 Oct;297(4):101175. doi: 10.1016/j.jbc.2021.101175. Epub 2021 Sep 7. J Biol Chem. 2021. PMID: 34499924 Free PMC article.

2

High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding partners.

Alonso LG, García-Alai MM, Nadra AD, Lapeña AN, Almeida FL, Gualfetti P, Prat-Gay GD. Alonso LG, et al. Biochemistry. 2002 Aug 20;41(33):10510-8. doi: 10.1021/bi025579n. Biochemistry. 2002. PMID: 12173938

3

The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.

Alonso LG, García-Alai MM, Smal C, Centeno JM, Iacono R, Castaño E, Gualfetti P, de Prat-Gay G. Alonso LG, et al. Biochemistry. 2004 Mar 30;43(12):3310-7. doi: 10.1021/bi036037o. Biochemistry. 2004. PMID: 15035602

4

Chaperone holdase activity of human papillomavirus E7 oncoprotein.

Alonso LG, Smal C, Garcia-Alai MM, Chemes L, Salame M, de Prat-Gay G. Alonso LG, et al. Biochemistry. 2006 Jan 24;45(3):657-67. doi: 10.1021/bi0522549. Biochemistry. 2006. PMID: 16411741

5

The N-terminal module of HPV16 E7 is an intrinsically disordered domain that confers conformational and recognition plasticity to the oncoprotein.

García-Alai MM, Alonso LG, de Prat-Gay G. García-Alai MM, et al. Among authors: alonso lg. Biochemistry. 2007 Sep 18;46(37):10405-12. doi: 10.1021/bi7007917. Epub 2007 Aug 23. Biochemistry. 2007. PMID: 17715947

6

The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.

Llovera RE, de Tullio M, Alonso LG, Leissring MA, Kaufman SB, Roher AE, de Prat Gay G, Morelli L, Castaño EM. Llovera RE, et al. Among authors: alonso lg. J Biol Chem. 2008 Jun 20;283(25):17039-48. doi: 10.1074/jbc.M706316200. Epub 2008 Apr 14. J Biol Chem. 2008. PMID: 18411275 Free article.

7

The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins.

Smal C, Wetzler DE, Dantur KI, Chemes LB, Garcia-Alai MM, Dellarole M, Alonso LG, Gaston K, de Prat-Gay G. Smal C, et al. Among authors: alonso lg. Biochemistry. 2009 Dec 22;48(50):11939-49. doi: 10.1021/bi901415k. Biochemistry. 2009. PMID: 19899811

8

Sequence evolution of the intrinsically disordered and globular domains of a model viral oncoprotein.

Chemes LB, Glavina J, Alonso LG, Marino-Buslje C, de Prat-Gay G, Sánchez IE. Chemes LB, et al. Among authors: alonso lg. PLoS One. 2012;7(10):e47661. doi: 10.1371/journal.pone.0047661. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23118886 Free PMC article.

9

Cysteine-rich positions outside the structural zinc motif of human papillomavirus E7 provide conformational modulation and suggest functional redox roles.

Chemes LB, Camporeale G, Sánchez IE, de Prat-Gay G, Alonso LG. Chemes LB, et al. Among authors: alonso lg. Biochemistry. 2014 Mar 18;53(10):1680-96. doi: 10.1021/bi401562e. Epub 2014 Mar 6. Biochemistry. 2014. PMID: 24559112

10

Amino Acid metabolism conflicts with protein diversity.

Krick T, Verstraete N, Alonso LG, Shub DA, Ferreiro DU, Shub M, Sánchez IE. Krick T, et al. Among authors: alonso lg. Mol Biol Evol. 2014 Nov;31(11):2905-12. doi: 10.1093/molbev/msu228. Epub 2014 Aug 1. Mol Biol Evol. 2014. PMID: 25086000 Free PMC article.

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