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Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.
Daude N, Ng V, Watts JC, Genovesi S, Glaves JP, Wohlgemuth S, Schmitt-Ulms G, Young H, McLaurin J, Fraser PE, Westaway D. Daude N, et al. Among authors: wohlgemuth s. J Neurochem. 2010 Apr;113(1):92-104. doi: 10.1111/j.1471-4159.2010.06575.x. Epub 2010 Jan 8. J Neurochem. 2010. PMID: 20067571 Free article.
The PrP-like proteins Shadoo and Doppel.
Westaway D, Daude N, Wohlgemuth S, Harrison P. Westaway D, et al. Among authors: wohlgemuth s. Top Curr Chem. 2011;305:225-56. doi: 10.1007/128_2011_190. Top Curr Chem. 2011. PMID: 21728138 Review.
Endoproteolytic processing of the mammalian prion glycoprotein family.
Mays CE, Coomaraswamy J, Watts JC, Yang J, Ko KW, Strome B, Mercer RC, Wohlgemuth SL, Schmitt-Ulms G, Westaway D. Mays CE, et al. Among authors: wohlgemuth sl. FEBS J. 2014 Feb;281(3):862-76. doi: 10.1111/febs.12654. Epub 2013 Dec 23. FEBS J. 2014. PMID: 24286250 Free article.
Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.
Lau A, McDonald A, Daude N, Mays CE, Walter ED, Aglietti R, Mercer RC, Wohlgemuth S, van der Merwe J, Yang J, Gapeshina H, Kim C, Grams J, Shi B, Wille H, Balachandran A, Schmitt-Ulms G, Safar JG, Millhauser GL, Westaway D. Lau A, et al. Among authors: wohlgemuth s. EMBO Mol Med. 2015 Mar;7(3):339-56. doi: 10.15252/emmm.201404588. EMBO Mol Med. 2015. PMID: 25661904 Free PMC article.
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.
Mercer RCC, Daude N, Dorosh L, Fu ZL, Mays CE, Gapeshina H, Wohlgemuth SL, Acevedo-Morantes CY, Yang J, Cashman NR, Coulthart MB, Pearson DM, Joseph JT, Wille H, Safar JG, Jansen GH, Stepanova M, Sykes BD, Westaway D. Mercer RCC, et al. PLoS Pathog. 2018 Jan 16;14(1):e1006826. doi: 10.1371/journal.ppat.1006826. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29338055 Free PMC article.
150 results