Wu X - Search Results

1

A second S4 movement opens hyperpolarization-activated HCN channels.

Wu X, Ramentol R, Perez ME, Noskov SY, Larsson HP. Wu X, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2102036118. doi: 10.1073/pnas.2102036118. Proc Natl Acad Sci U S A. 2021. PMID: 34504015 Free PMC article.

2

Polyunsaturated fatty acids produce a range of activators for heterogeneous IKs channel dysfunction.

Bohannon BM, Wu X, Wu X, Perez ME, Liin SI, Larsson HP. Bohannon BM, et al. Among authors: wu x. J Gen Physiol. 2020 Feb 3;152(2):e201912396. doi: 10.1085/jgp.201912396. J Gen Physiol. 2020. PMID: 31865382 Free PMC article.

3

Polyunsaturated fatty acid analogues differentially affect cardiac Na_V, Ca_V, and K_V channels through unique mechanisms.

Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP. Bohannon BM, et al. Among authors: wu x. Elife. 2020 Mar 24;9:e51453. doi: 10.7554/eLife.51453. Elife. 2020. PMID: 32207683 Free PMC article.

4

Correction: Polyunsaturated fatty acid analogues differentially affect cardiac Na_V, Ca_V, and K_V channels through unique mechanisms.

Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP. Bohannon BM, et al. Among authors: wu x. Elife. 2020 Jun 18;9:e60141. doi: 10.7554/eLife.60141. Elife. 2020. PMID: 32553105 Free PMC article.

5

Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation.

Wu X, Larsson HP. Wu X, et al. Int J Mol Sci. 2020 Dec 11;21(24):9440. doi: 10.3390/ijms21249440. Int J Mol Sci. 2020. PMID: 33322401 Free PMC article. Review.

6

A general mechanism of KCNE1 modulation of KCNQ1 channels involving non-canonical VSD-PD coupling.

Wu X, Perez ME, Noskov SY, Larsson HP. Wu X, et al. Commun Biol. 2021 Jul 20;4(1):887. doi: 10.1038/s42003-021-02418-1. Commun Biol. 2021. PMID: 34285340 Free PMC article.

7

Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels.

Edmond MA, Hinojo-Perez A, Wu X, Perez Rodriguez ME, Barro-Soria R. Edmond MA, et al. Among authors: wu x. Elife. 2022 Jun 1;11:e77030. doi: 10.7554/eLife.77030. Elife. 2022. PMID: 35642783 Free PMC article.

8

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels.

Zou X, Wu X, Sampson KJ, Colecraft HM, Larsson HP, Kass RS. Zou X, et al. Among authors: wu x. Front Physiol. 2022 Nov 23;13:902224. doi: 10.3389/fphys.2022.902224. eCollection 2022. Front Physiol. 2022. PMID: 36505078 Free PMC article.

9

Similar voltage-sensor movement in spHCN channels can cause closing, opening, or inactivation.

Wu X, Cunningham KP, Ramentol R, Perez ME, Larsson HP. Wu X, et al. J Gen Physiol. 2023 May 1;155(5):e202213170. doi: 10.1085/jgp.202213170. Epub 2023 Feb 8. J Gen Physiol. 2023. PMID: 36752823 Free PMC article.

10

Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart.

De la Cruz A, Wu X, Rainer QC, Hiniesto-Iñigo I, Perez ME, Edler I, Liin SI, Larsson HP. De la Cruz A, et al. Among authors: wu x. Int J Mol Sci. 2023 Jul 28;24(15):12092. doi: 10.3390/ijms241512092. Int J Mol Sci. 2023. PMID: 37569465 Free PMC article.

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