Malhotra V - Search Results

1

A Low-Prevalence Single-Nucleotide Polymorphism in the Sensor Kinase PhoR in Mycobacterium tuberculosis Suppresses Its Autophosphatase Activity and Reduces Pathogenic Fitness: Implications in Evolutionary Selection.

Waturuocha UW, Krishna MS, Malhotra V, Dixit NM, Saini DK. Waturuocha UW, et al. Among authors: malhotra v. Front Microbiol. 2021 Aug 25;12:724482. doi: 10.3389/fmicb.2021.724482. eCollection 2021. Front Microbiol. 2021. PMID: 34512602 Free PMC article.

2

A high-frequency single nucleotide polymorphism in the MtrB sensor kinase in clinical strains of Mycobacterium tuberculosis alters its biochemical and physiological properties.

Waturuocha UW, P J A, Singh KK, Malhotra V, Krishna MS, Saini DK. Waturuocha UW, et al. Among authors: malhotra v. PLoS One. 2021 Sep 16;16(9):e0256664. doi: 10.1371/journal.pone.0256664. eCollection 2021. PLoS One. 2021. PMID: 34529706 Free PMC article.

3

DevR-DevS is a bona fide two-component system of Mycobacterium tuberculosis that is hypoxia-responsive in the absence of the DNA-binding domain of DevR.

Saini DK, Malhotra V, Dey D, Pant N, Das TK, Tyagi JS. Saini DK, et al. Among authors: malhotra v. Microbiology (Reading). 2004 Apr;150(Pt 4):865-875. doi: 10.1099/mic.0.26218-0. Microbiology (Reading). 2004. PMID: 15073296 Free article.

4

Mycobacterium tuberculosis PknK Substrate Profiling Reveals Essential Transcription Terminator Protein Rho and Two-Component Response Regulators PrrA and MtrA as Novel Targets for Phosphorylation.

Malhotra V, Okon BP, Satsangi AT, Das S, Waturuocha UW, Vashist A, Clark-Curtiss JE, Saini DK. Malhotra V, et al. Microbiol Spectr. 2022 Apr 27;10(2):e0135421. doi: 10.1128/spectrum.01354-21. Epub 2022 Apr 11. Microbiol Spectr. 2022. PMID: 35404097 Free PMC article.

5

Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis.

Malhotra V, Sharma D, Ramanathan VD, Shakila H, Saini DK, Chakravorty S, Das TK, Li Q, Silver RF, Narayanan PR, Tyagi JS. Malhotra V, et al. FEMS Microbiol Lett. 2004 Feb 16;231(2):237-45. doi: 10.1016/S0378-1097(04)00002-3. FEMS Microbiol Lett. 2004. PMID: 14987770

6

Cross talk between DevS sensor kinase homologue, Rv2027c, and DevR response regulator of Mycobacterium tuberculosis.

Saini DK, Malhotra V, Tyagi JS. Saini DK, et al. Among authors: malhotra v. FEBS Lett. 2004 May 7;565(1-3):75-80. doi: 10.1016/j.febslet.2004.02.092. FEBS Lett. 2004. PMID: 15135056 Free article.

7

Acetylation of Response Regulator Proteins, TcrX and MtrA in M. tuberculosis Tunes their Phosphotransfer Ability and Modulates Two-Component Signaling Crosstalk.

Singh KK, Bhardwaj N, Sankhe GD, Udaykumar N, Singh R, Malhotra V, Saini DK. Singh KK, et al. Among authors: malhotra v. J Mol Biol. 2019 Feb 15;431(4):777-793. doi: 10.1016/j.jmb.2019.01.004. Epub 2019 Jan 9. J Mol Biol. 2019. PMID: 30639188

8

Cyclic di-GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources.

Hariharan VN, Yadav R, Thakur C, Singh A, Gopinathan R, Singh DP, Sankhe G, Malhotra V, Chandra N, Bhatt A, Saini DK. Hariharan VN, et al. Among authors: malhotra v. FASEB J. 2021 Apr;35(4):e21475. doi: 10.1096/fj.202002537RR. FASEB J. 2021. PMID: 33772870

9

Mycobacterium tuberculosis response regulators, DevR and NarL, interact in vivo and co-regulate gene expression during aerobic nitrate metabolism.

Malhotra V, Agrawal R, Duncan TR, Saini DK, Clark-Curtiss JE. Malhotra V, et al. J Biol Chem. 2015 Mar 27;290(13):8294-309. doi: 10.1074/jbc.M114.591800. Epub 2015 Feb 6. J Biol Chem. 2015. PMID: 25659431 Free PMC article.

10

Erratum to: The Mycobacterium tuberculosis relBE toxin: antitoxin genes are stress-responsive modules that regulate growth through translation inhibition.

Korch SB, Malhotra V, Contreras H, Clark-Curtiss JE. Korch SB, et al. Among authors: malhotra v. J Microbiol. 2015 Dec;53(12):875. doi: 10.1007/s12275-015-0741-3. J Microbiol. 2015. PMID: 26626358 No abstract available.

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