Dos Santos CO - Search Results

1

New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.

Zahid H, Buchholz CR, Singh M, Ciccone MF, Chan A, Nithianantham S, Shi K, Aihara H, Fischer M, Schönbrunn E, Dos Santos CO, Landry JW, Pomerantz WCK. Zahid H, et al. Among authors: dos santos co. J Med Chem. 2021 Sep 23;64(18):13902-13917. doi: 10.1021/acs.jmedchem.1c01294. Epub 2021 Sep 13. J Med Chem. 2021. PMID: 34515477 Free PMC article.

2

Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules.

Urick AK, Hawk LM, Cassel MK, Mishra NK, Liu S, Adhikari N, Zhang W, dos Santos CO, Hall JL, Pomerantz WC. Urick AK, et al. Among authors: dos santos co. ACS Chem Biol. 2015 Oct 16;10(10):2246-56. doi: 10.1021/acschembio.5b00483. Epub 2015 Jul 28. ACS Chem Biol. 2015. PMID: 26158404 Free PMC article.

3

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

Frey WD, Chaudhry A, Slepicka PF, Ouellette AM, Kirberger SE, Pomerantz WCK, Hannon GJ, Dos Santos CO. Frey WD, et al. Among authors: dos santos co. Stem Cell Reports. 2017 Jul 11;9(1):23-31. doi: 10.1016/j.stemcr.2017.04.031. Epub 2017 Jun 1. Stem Cell Reports. 2017. PMID: 28579392 Free PMC article.

4

Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.

Kirberger SE, Ycas PD, Johnson JA, Chen C, Ciccone MF, Woo RWL, Urick AK, Zahid H, Shi K, Aihara H, McAllister SD, Kashani-Sabet M, Shi J, Dickson A, Dos Santos CO, Pomerantz WCK. Kirberger SE, et al. Among authors: dos santos co. Org Biomol Chem. 2019 Feb 13;17(7):2020-2027. doi: 10.1039/c8ob02599a. Org Biomol Chem. 2019. PMID: 30706071 Free PMC article.

5

Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions.

Feigman MJ, Moss MA, Chen C, Cyrill SL, Ciccone MF, Trousdell MC, Yang ST, Frey WD, Wilkinson JE, Dos Santos CO. Feigman MJ, et al. Among authors: dos santos co. Nat Commun. 2020 May 27;11(1):2649. doi: 10.1038/s41467-020-16479-z. Nat Commun. 2020. PMID: 32461571 Free PMC article.

6

Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells.

Ciccone MF, Trousdell MC, Dos Santos CO. Ciccone MF, et al. Among authors: dos santos co. J Mammary Gland Biol Neoplasia. 2020 Dec;25(4):351-366. doi: 10.1007/s10911-020-09465-0. Epub 2020 Nov 1. J Mammary Gland Biol Neoplasia. 2020. PMID: 33131024 Free PMC article. Review.

7

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis.

Hanasoge Somasundara AV, Moss MA, Feigman MJ, Chen C, Cyrill SL, Ciccone MF, Trousdell MC, Vollbrecht M, Li S, Kendall J, Beyaz S, Wilkinson JE, Dos Santos CO. Hanasoge Somasundara AV, et al. Among authors: dos santos co. Cell Rep. 2021 Dec 7;37(10):110099. doi: 10.1016/j.celrep.2021.110099. Cell Rep. 2021. PMID: 34879282 Free PMC article.

8

Cathepsin B Is Not an Intrinsic Factor Related to Asparaginase Resistance of the Acute Lymphoblastic Leukemia REH Cell Line.

Costa IM, Effer B, Costa-Silva TA, Chen C, Ciccone MF, Pessoa A, Dos Santos CO, Monteiro G. Costa IM, et al. Among authors: dos santos co. Int J Mol Sci. 2023 Jul 7;24(13):11215. doi: 10.3390/ijms241311215. Int J Mol Sci. 2023. PMID: 37446393 Free PMC article.

9

Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones.

Ortiz JR, Lewis SM, Ciccone M, Chatterjee D, Henry S, Siepel A, Dos Santos CO. Ortiz JR, et al. Among authors: dos santos co. J Mammary Gland Biol Neoplasia. 2024 Jan 30;29(1):3. doi: 10.1007/s10911-023-09553-x. J Mammary Gland Biol Neoplasia. 2024. PMID: 38289401 Free PMC article.

10

Single-cell transcription mapping of murine and human mammary organoids responses to female hormones.

Ortiz JR, Lewis SM, Ciccone MF, Chatterjee D, Henry S, Siepel A, Dos Santos CO. Ortiz JR, et al. Among authors: dos santos co. bioRxiv [Preprint]. 2023 Sep 29:2023.09.28.559971. doi: 10.1101/2023.09.28.559971. bioRxiv. 2023. Update in: J Mammary Gland Biol Neoplasia. 2024 Jan 30;29(1):3. doi: 10.1007/s10911-023-09553-x PMID: 37808747 Free PMC article. Updated. Preprint.

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