Flora GD - Search Results

1

PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic stroke.

Dhanesha N, Patel RB, Doddapattar P, Ghatge M, Flora GD, Jain M, Thedens D, Olalde H, Kumskova M, Leira EC, Chauhan AK. Dhanesha N, et al. Among authors: flora gd. Blood. 2022 Feb 24;139(8):1234-1245. doi: 10.1182/blood.2021012322. Blood. 2022. PMID: 34529778 Free PMC article.

2

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice.

Dhanesha N, Nayak MK, Doddapattar P, Jain M, Flora GD, Kon S, Chauhan AK. Dhanesha N, et al. Among authors: flora gd. Blood. 2020 Mar 12;135(11):857-861. doi: 10.1182/blood.2019002846. Blood. 2020. PMID: 31951649 Free PMC article.

3

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.

Sahli KA, Flora GD, Sasikumar P, Maghrabi AH, Holbrook LM, AlOuda SK, Elgheznawy A, Sage T, Stainer AR, Adiyaman R, AboHassan M, Crescente M, Kriek N, Vaiyapuri S, Bye AP, Unsworth AJ, Jones CI, McGuffin LJ, Gibbins JM. Sahli KA, et al. Among authors: flora gd. Blood. 2021 Feb 11;137(6):830-843. doi: 10.1182/blood.2019004575. Blood. 2021. PMID: 32822477 Free PMC article.

4

The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis.

Nayak MK, Ghatge M, Flora GD, Dhanesha N, Jain M, Markan KR, Potthoff MJ, Lentz SR, Chauhan AK. Nayak MK, et al. Among authors: flora gd. Blood. 2021 Mar 25;137(12):1658-1668. doi: 10.1182/blood.2020007140. Blood. 2021. PMID: 33027814 Free PMC article.

5

Constitutively active ADAMTS13: An emerging thrombolytic agent for acute ischemic stroke.

Nayak MK, Flora GD, Chauhan AK. Nayak MK, et al. Among authors: flora gd. J Thromb Haemost. 2022 Apr;20(4):790-793. doi: 10.1111/jth.15649. Epub 2022 Feb 2. J Thromb Haemost. 2022. PMID: 35106938 Free PMC article. No abstract available.

6

Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis.

Flora GD, Nayak MK, Ghatge M, Kumskova M, Patel RB, Chauhan AK. Flora GD, et al. Blood Adv. 2023 Jun 13;7(11):2347-2359. doi: 10.1182/bloodadvances.2023010100. Blood Adv. 2023. PMID: 36971790 Free PMC article.

7

Mitochondrial calcium uniporter b deletion inhibits platelet function and reduces susceptibility to arterial thrombosis.

Ghatge M, Nayak MK, Flora GD, Kumskova M, Jain A, Patel RB, Lin Z, Usachev YM, Chauhan AK. Ghatge M, et al. Among authors: flora gd. J Thromb Haemost. 2023 Aug;21(8):2163-2174. doi: 10.1016/j.jtha.2023.04.002. Epub 2023 Apr 13. J Thromb Haemost. 2023. PMID: 37061131 Free article.

8

Metabolic targeting of platelets to combat thrombosis: dawn of a new paradigm?

Flora GD, Nayak MK, Ghatge M, Chauhan AK. Flora GD, et al. Cardiovasc Res. 2023 Nov 25;119(15):2497-2507. doi: 10.1093/cvr/cvad149. Cardiovasc Res. 2023. PMID: 37706546 Free PMC article. Review.

9

Platelet Metabolic Profiling Reveals Glycolytic and 1-Carbon Metabolites Are Essential for GP VI-Stimulated Human Platelets-Brief Report.

Ghatge M, Flora GD, Nayak MK, Chauhan AK. Ghatge M, et al. Among authors: flora gd. Arterioscler Thromb Vasc Biol. 2024 Feb;44(2):409-416. doi: 10.1161/ATVBAHA.123.319821. Epub 2023 Nov 9. Arterioscler Thromb Vasc Biol. 2024. PMID: 37942614 Free article.

10

Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.

Flora GD, Sahli KA, Sasikumar P, Holbrook LM, Stainer AR, AlOuda SK, Crescente M, Sage T, Unsworth AJ, Gibbins JM. Flora GD, et al. Sci Rep. 2019 Nov 20;9(1):17210. doi: 10.1038/s41598-019-53218-x. Sci Rep. 2019. PMID: 31748641 Free PMC article.

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