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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
Herviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J. Herviou L, et al. Among authors: vincent l. Clin Epigenetics. 2021 Sep 16;13(1):174. doi: 10.1186/s13148-021-01160-z. Clin Epigenetics. 2021. PMID: 34530900 Free PMC article.
Differential effects of lenalidomide during plasma cell differentiation.
Jourdan M, Cren M, Schafer P, Robert N, Duperray C, Vincent L, Ceballos P, Cartron G, Rossi JF, Moreaux J, Chopra R, Klein B. Jourdan M, et al. Among authors: vincent l. Oncotarget. 2016 May 10;7(19):28096-111. doi: 10.18632/oncotarget.8581. Oncotarget. 2016. PMID: 27057635 Free PMC article.
DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells.
Bruyer A, Maes K, Herviou L, Kassambara A, Seckinger A, Cartron G, Rème T, Robert N, Requirand G, Boireau S, Müller-Tidow C, Veyrune JL, Vincent L, Bouhya S, Goldschmidt H, Vanderkerken K, Hose D, Klein B, De Bruyne E, Moreaux J. Bruyer A, et al. Among authors: vincent l. Br J Cancer. 2018 Apr;118(8):1062-1073. doi: 10.1038/s41416-018-0025-x. Epub 2018 Mar 2. Br J Cancer. 2018. PMID: 29500406 Free PMC article.
PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs.
Herviou L, Kassambara A, Boireau S, Robert N, Requirand G, Müller-Tidow C, Vincent L, Seckinger A, Goldschmidt H, Cartron G, Hose D, Cavalli G, Moreaux J. Herviou L, et al. Among authors: vincent l. Clin Epigenetics. 2018 Oct 3;10(1):121. doi: 10.1186/s13148-018-0554-4. Clin Epigenetics. 2018. PMID: 30285865 Free PMC article.
567 results