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A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Igelmann S, Lessard F, Uchenunu O, Bouchard J, Fernandez-Ruiz A, Rowell MC, Lopes-Paciencia S, Papadopoli D, Fouillen A, Ponce KJ, Huot G, Mignacca L, Benfdil M, Kalegari P, Wahba HM, Pencik J, Vuong N, Quenneville J, Guillon J, Bourdeau V, Hulea L, Gagnon E, Kenner L, Moriggl R, Nanci A, Pollak MN, Omichinski JG, Topisirovic I, Ferbeyre G. Igelmann S, et al. Mol Cell. 2021 Sep 16;81(18):3848-3865.e19. doi: 10.1016/j.molcel.2021.08.028. Mol Cell. 2021. PMID: 34547241 Free article.
Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer.
Rowell MC, Deschênes-Simard X, Lopes-Paciencia S, Le Calvé B, Kalegari P, Mignacca L, Fernandez-Ruiz A, Guillon J, Lessard F, Bourdeau V, Igelmann S, Duman AM, Stanom Y, Kottakis F, Deshpande V, Krizhanovsky V, Bardeesy N, Ferbeyre G. Rowell MC, et al. Among authors: fernandez ruiz a. Cell Cycle. 2023 Oct;22(19):2172-2193. doi: 10.1080/15384101.2023.2278945. Epub 2023 Dec 5. Cell Cycle. 2023. PMID: 37942963 Free PMC article.
Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI.
Tiwari P, Davoudian PA, Kapri D, Vuruputuri RM, Karaba LA, Sharma M, Zanni G, Balakrishnan A, Chaudhari PR, Pradhan A, Suryavanshi S, Bath KG, Ansorge MS, Fernandez-Ruiz A, Kwan AC, Vaidya VA. Tiwari P, et al. Among authors: fernandez ruiz a. Neuron. 2024 Nov 20;112(22):3697-3714.e6. doi: 10.1016/j.neuron.2024.08.016. Epub 2024 Sep 24. Neuron. 2024. PMID: 39321791
Interictal epileptiform discharges affect memory in an Alzheimer's disease mouse model.
Soula M, Maslarova A, Harvey RE, Valero M, Brandner S, Hamer H, Fernández-Ruiz A, Buzsáki G. Soula M, et al. Among authors: fernandez ruiz a. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302676120. doi: 10.1073/pnas.2302676120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590406 Free PMC article.
65 results