Gaddam RR - Search Results

1

Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid-Based Oncomir Inhibitors for Cancer Therapy.

Dhuri K, Gaddam RR, Vikram A, Slack FJ, Bahal R. Dhuri K, et al. Among authors: gaddam rr. Cancer Res. 2021 Nov 15;81(22):5613-5624. doi: 10.1158/0008-5472.CAN-21-0736. Epub 2021 Sep 21. Cancer Res. 2021. PMID: 34548334 Free PMC article.

2

SUMO2 regulates vascular endothelial function and oxidative stress in mice.

Kim YR, Jacobs JS, Li Q, Gaddam RR, Vikram A, Liu J, Kassan M, Irani K, Kumar S. Kim YR, et al. Among authors: gaddam rr. Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1292-H1300. doi: 10.1152/ajpheart.00530.2019. Epub 2019 Oct 4. Am J Physiol Heart Circ Physiol. 2019. PMID: 31584834 Free PMC article.

3

Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice.

Gaddam RR, Jacobsen VP, Kim YR, Gabani M, Jacobs JS, Dhuri K, Kumar S, Kassan M, Li Q, Bahal R, Roghair R, Irani K, Vikram A. Gaddam RR, et al. Sci Rep. 2020 Jun 22;10(1):10065. doi: 10.1038/s41598-020-66786-0. Sci Rep. 2020. PMID: 32572127 Free PMC article.

4

Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice.

Gaddam RR, Kim YR, Li Q, Jacobs JS, Gabani M, Mishra A, Promes JA, Imai Y, Irani K, Vikram A. Gaddam RR, et al. Biochem Biophys Res Commun. 2020 Nov 5;532(2):167-172. doi: 10.1016/j.bbrc.2020.08.077. Epub 2020 Sep 17. Biochem Biophys Res Commun. 2020. PMID: 32950230 Free PMC article.

5

Dual-Modality Poly-l-histidine Nanoparticles to Deliver Peptide Nucleic Acids and Paclitaxel for In Vivo Cancer Therapy.

Wahane A, Malik S, Shih KC, Gaddam RR, Chen C, Liu Y, Nieh MP, Vikram A, Bahal R. Wahane A, et al. Among authors: gaddam rr. ACS Appl Mater Interfaces. 2021 Sep 29;13(38):45244-45258. doi: 10.1021/acsami.1c11981. Epub 2021 Sep 15. ACS Appl Mater Interfaces. 2021. PMID: 34524806

6

The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint.

Momin MY, Gaddam RR, Kravitz M, Gupta A, Vikram A. Momin MY, et al. Among authors: gaddam rr. Cells. 2021 Nov 9;10(11):3097. doi: 10.3390/cells10113097. Cells. 2021. PMID: 34831320 Free PMC article. Review.

7

The microRNA-204-5p inhibits APJ signalling and confers resistance to cardiac hypertrophy and dysfunction.

Gaddam RR, Kim YR, Jacobs JS, Yoon JY, Li Q, Cai A, Shankaiahgari H, London B, Irani K, Vikram A. Gaddam RR, et al. Clin Transl Med. 2022 Jan;12(1):e693. doi: 10.1002/ctm2.693. Clin Transl Med. 2022. PMID: 35060347 Free PMC article.

8

γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet.

Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R, Vikram A. Gaddam RR, et al. J Med Chem. 2022 Feb 24;65(4):3332-3342. doi: 10.1021/acs.jmedchem.1c01831. Epub 2022 Feb 8. J Med Chem. 2022. PMID: 35133835 Free PMC article.

9

Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking.

Gundu C, Arruri VK, Yadav P, Navik U, Kumar A, Amalkar VS, Vikram A, Gaddam RR. Gundu C, et al. Among authors: gaddam rr. Cells. 2022 Aug 17;11(16):2557. doi: 10.3390/cells11162557. Cells. 2022. PMID: 36010634 Free PMC article. Review.

10

Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.

Li Q, Zhang Q, Kim YR, Gaddam RR, Jacobs JS, Bachschmid MM, Younis T, Zhu Z, Zingman L, London B, Rauckhorst AJ, Taylor EB, Norris AW, Vikram A, Irani K. Li Q, et al. Among authors: gaddam rr. Nat Commun. 2023 Sep 11;14(1):5595. doi: 10.1038/s41467-023-41351-1. Nat Commun. 2023. PMID: 37696839 Free PMC article.

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