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Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Jiang S, Maphis NM, Binder J, Chisholm D, Weston L, Duran W, Peterson C, Zimmerman A, Mandell MA, Jett SD, Bigio E, Geula C, Mellios N, Weick JP, Rosenberg GA, Latz E, Heneka MT, Bhaskar K. Jiang S, et al. Among authors: binder j. Cell Rep. 2021 Sep 21;36(12):109720. doi: 10.1016/j.celrep.2021.109720. Cell Rep. 2021. PMID: 34551296 Free PMC article.
Getting Started with the IDG KMC Datasets and Tools.
Kropiwnicki E, Binder JL, Yang JJ, Holmes J, Lachmann A, Clarke DJB, Sheils T, Kelleher KJ, Metzger VT, Bologa CG, Oprea TI, Ma'ayan A. Kropiwnicki E, et al. Among authors: binder jl. Curr Protoc. 2022 Jan;2(1):e355. doi: 10.1002/cpz1.355. Curr Protoc. 2022. PMID: 35085427 Free PMC article.
AlphaFold illuminates half of the dark human proteins.
Binder JL, Berendzen J, Stevens AO, He Y, Wang J, Dokholyan NV, Oprea TI. Binder JL, et al. Curr Opin Struct Biol. 2022 Jun;74:102372. doi: 10.1016/j.sbi.2022.102372. Epub 2022 Apr 16. Curr Opin Struct Biol. 2022. PMID: 35439658 Free PMC article. Review.
569 results