Qu CK - Search Results

1

JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β.

Yan Y, Dong L, Chen C, Bunting KD, Li Q, Stieglitz E, Loh ML, Qu CK. Yan Y, et al. Among authors: qu ck. Blood Adv. 2022 Jan 11;6(1):200-206. doi: 10.1182/bloodadvances.2021005089. Blood Adv. 2022. PMID: 34555844 Free PMC article.

2

A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival.

Chen J, Yu WM, Bunting KD, Qu CK. Chen J, et al. Among authors: qu ck. Oncogene. 2004 Apr 29;23(20):3659-69. doi: 10.1038/sj.onc.1207471. Oncogene. 2004. PMID: 15116097

3

Increased numbers of committed myeloid progenitors but not primitive hematopoietic stem/progenitors in mice lacking STAT6 expression.

Bunting KD, Yu WM, Bradley HL, Haviernikova E, Kelly-Welch AE, Keegan AD, Qu CK. Bunting KD, et al. Among authors: qu ck. J Leukoc Biol. 2004 Aug;76(2):484-90. doi: 10.1189/jlb.0903440. Epub 2004 May 3. J Leukoc Biol. 2004. PMID: 15123777

4

Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling.

Yu WM, Daino H, Chen J, Bunting KD, Qu CK. Yu WM, et al. Among authors: qu ck. J Biol Chem. 2006 Mar 3;281(9):5426-34. doi: 10.1074/jbc.M507622200. Epub 2005 Dec 21. J Biol Chem. 2006. PMID: 16371368 Free article.

5

Abnormal hematopoiesis in Gab2 mutant mice.

Zhang Y, Diaz-Flores E, Li G, Wang Z, Kang Z, Haviernikova E, Rowe S, Qu CK, Tse W, Shannon KM, Bunting KD. Zhang Y, et al. Among authors: qu ck. Blood. 2007 Jul 1;110(1):116-24. doi: 10.1182/blood-2006-11-060707. Epub 2007 Mar 20. Blood. 2007. PMID: 17374739 Free PMC article.

6

A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.

Xu D, Wang S, Yu WM, Chan G, Araki T, Bunting KD, Neel BG, Qu CK. Xu D, et al. Among authors: qu ck. Blood. 2010 Nov 4;116(18):3611-21. doi: 10.1182/blood-2010-01-265652. Epub 2010 Jul 22. Blood. 2010. PMID: 20651068 Free PMC article.

7

Molecular targets for the treatment of juvenile myelomonocytic leukemia.

Liu X, Sabnis H, Bunting KD, Qu CK. Liu X, et al. Among authors: qu ck. Adv Hematol. 2012;2012:308252. doi: 10.1155/2012/308252. Epub 2011 Nov 13. Adv Hematol. 2012. PMID: 22162691 Free PMC article.

8

Molecular-targeted therapies for hematologic malignancies.

Bunting KD, Qu CK, Tomasson MH. Bunting KD, et al. Among authors: qu ck. Adv Hematol. 2012;2012:606423. doi: 10.1155/2012/606423. Epub 2011 Dec 28. Adv Hematol. 2012. PMID: 22242021 Free PMC article. No abstract available.

9

Targeting protein tyrosine phosphatase SHP2 for the treatment of PTPN11-associated malignancies.

Yu B, Liu W, Yu WM, Loh ML, Alter S, Guvench O, Mackerell AD Jr, Tang LD, Qu CK. Yu B, et al. Among authors: qu ck. Mol Cancer Ther. 2013 Sep;12(9):1738-48. doi: 10.1158/1535-7163.MCT-13-0049-T. Epub 2013 Jul 3. Mol Cancer Ther. 2013. PMID: 23825065 Free PMC article.

10

Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).

Liu W, Yu B, Xu G, Xu WR, Loh ML, Tang LD, Qu CK. Liu W, et al. Among authors: qu ck. J Med Chem. 2013 Sep 26;56(18):7212-21. doi: 10.1021/jm400474r. Epub 2013 Sep 4. J Med Chem. 2013. PMID: 23957426 Free PMC article.

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