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Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II.
Radnai L, Surman M, Hafenbreidel M, Young EJ, Stremel RF, Lin L, Bdiri B, Pasetto P, Jin X, Geedy M, Partridge JR, Patel A, Conlon M, Sellers JR, Cameron MD, Rumbaugh G, Griffin PR, Kamenecka TM, Miller CA. Radnai L, et al. Among authors: geedy m. ACS Chem Biol. 2021 Nov 19;16(11):2164-2173. doi: 10.1021/acschembio.1c00067. Epub 2021 Sep 24. ACS Chem Biol. 2021. PMID: 34558887
GAC inhibitors with a 4-hydroxypiperidine spacer: Requirements for potency.
McDermott L, Koes D, Mohammed S, Iyer P, Boby M, Balasubramanian V, Geedy M, Katt W, Cerione R. McDermott L, et al. Among authors: geedy m. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126632. doi: 10.1016/j.bmcl.2019.126632. Epub 2019 Aug 20. Bioorg Med Chem Lett. 2019. PMID: 31474484 Free PMC article.